Stark zytotoxisch ist die Titelverbindung 1. Die erste Totalsynthese dieses Naturstoffs beruht auf dem effizienten Aufbau des anspruchsvollen (R,S)‐γClPip/(S,S)‐γOHPip‐Dipeptidfragments sowie einer Makrocyclisierung durch die SN2‐Reaktion einer N‐2‐Chloracetyl‐Einheit mit einem Carboxylat‐Ion.
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