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한양대학교 자동차전자 제어연구소 Abstract : In this study, we presented a timing verification method for a passenger car diesel engine management system (EMS) using measurement-based worst-case execution time (WCET) analysis. In order to cope with AUTOSAR-compliant software architecture, a development process model is proposed. In the process model, a runnable is regarded as a test unit and its temporal behavior (i.e. maximum observed execution time, MOET) is obtained along with on-target functionality evaluation results during online unit test. Furthermore, a cost-effective framework for online unit test is proposed. Because the runtime environment layer and the standard calibration environment are utilized to implement test interface, additional resource consumption of the target processor is minimized. Using the proposed development process model and unit test framework, the MOETs of 86 runnables for diesel EMS are obtained with 213 unit test cases. Using the obtained MOETs of runnables, the WCETs of tasks are estimated and the schedulability is evaluated. From the schedulability analysis results, the problems of the initially designed schedule table is recognized and it is fixed by redesigning of the runnable mapping and task offset. Through the various test scenarios, the proposed method is validated.

Purpose: Significant proportion of breast cancer patients with locoregional recurrence eventually die of their disease. This study was performed to investigate the risk factors associated with locoregional recurrence of breast cancer after breast conserving surgery. Methods: We reviewed the medical records of 302 patients with breast cancer who underwent breast conserving surgery and analyzed the association between locoregional recurrences and clinico-pathological factors of each patients. Results: The 26 of 302 patients (8.6%) developed locoregional recurrence during a median follow-up of 35.5 months. 18 patients (5.9%) had local recurrence, 6 patients (2.0%) had regional recurrence and 2 patients (0.7%) had locoregional recurrence. On univariate analysis, positive margin (p<0.0001), HER2/neu positive, extensive intraductal component, multiplicity were statistically significant risk factors for locoregional recurrence of breast cancer. On multivariate analysis, positive margin status, HER2/neu positivity and multiplicity were significantly associated with locoregional recurrence after breast conserving surgery. Conclusion: Our study showed that adequate resection margin is the most important to reduce locoregional recurrence of breast cancer after breast conserving surgery. In addition, HER2/neu amplification or multiplicity increased the locoregional recurrence rate in breast cancer.