1,3-Dithietane

Bioactive Four-Membered Heterocyclic Compounds: The Anti → Syn Interconversion in Dithietane-1,3-dioxide

“…The relative energy changes in solution (⌬GЊ soln. ) show that in a low polarity solvent such as CCl 4 , the concentration of II s is ca. 63%, whereas in a medium-high polarity solvents such as CH 3 CN and DMSO, this species is in ca.…”

“…Block et al (4,5) have prepared a series of S-oxides of 1,3-dithietane. Progressive oxidation of dithietane leads to mono, di, tri, and tetraoxides whose relevant structural features have been recently reported (6).…”

Introduction

“…1-1; Block et al, 1976c), The microwave spectrum of compound 1-4 revealed that it was puckered with the angle between the two CSC planes being 39.3° with oxygen equatorial as shown in l-4a. 1-1; Block et al, 1976c), The microwave spectrum of compound 1-4 revealed that it was puckered with the angle between the two CSC planes being 39.3° with oxygen equatorial as shown in l-4a.…”

“…1-1; Block et al, 1976c), The microwave spectrum of compound 1-4 revealed that it was puckered with the angle between the two CSC planes being 39.3° with oxygen equatorial as shown in l-4a. Table B-l), and (2) the S · S distance in bissulfone 1-9 is even shorter (2.590 Â as determined by x-ray crystallography) argues against any significant contribution from l-4b (Block et al, 1976c). However, the facts that (1) the S = 0 distance (1.473 Â) is normal or even slightly shorter than normal (cf.…”

“…The most intense lines in both the infrared and R a m a n spectra of the parent 1,3-dithietane 1-3 appear in the region 600-780 c m -1 , characteristic for G-S stretching modes (see Appendix B, Table B-5 ; for a current treatment of R a m a n spectroscopy of sulfur compounds, see Freeman, 1974). Symmetrical bissulfoxide 1-5 shows two S = 0 lines, perhaps as a result of coupled vibration of the two SO groups (Block et al, 1976c). Table B-4).…”