2021
DOI: 10.1016/s0140-6736(21)01755-4
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1-year outcomes in hospital survivors with COVID-19: a longitudinal cohort study

Abstract: Background The full range of long-term health consequences of COVID-19 in patients who are discharged from hospital is largely unclear. The aim of our study was to comprehensively compare consequences between 6 months and 12 months after symptom onset among hospital survivors with COVID-19. MethodsWe undertook an ambidirectional cohort study of COVID-19 survivors who had been discharged from Jin Yin-tan Hospital (Wuhan, China) between Jan 7 and May 29, 2020. At 6-month and 12-month follow-up visit, survivors w… Show more

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Cited by 888 publications
(1,172 citation statements)
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References 34 publications
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“…Using the same standardized questionnaires as used in our study, Huang et al showed in their prospective cohort study from Wuhan, China that 76% of convalescents reported at least one persistent symptom six months after symptom onset [7]. Quite recently, the same authors reported that one year after acute infection, COVID-19 survivors still had lower health status than did non-COVID-19 controls matched for age, sex, and comorbidities [12]. In a recent meta-analysis of 21 studies consisting of 47,910 patients (hospitalized and not hospitalized), 80% of patients with a confirmed COVID-19 diagnosis were reported to continue having at least one symptom beyond two weeks following acute infection [13].…”
Section: Discussionmentioning
confidence: 66%
See 1 more Smart Citation
“…Using the same standardized questionnaires as used in our study, Huang et al showed in their prospective cohort study from Wuhan, China that 76% of convalescents reported at least one persistent symptom six months after symptom onset [7]. Quite recently, the same authors reported that one year after acute infection, COVID-19 survivors still had lower health status than did non-COVID-19 controls matched for age, sex, and comorbidities [12]. In a recent meta-analysis of 21 studies consisting of 47,910 patients (hospitalized and not hospitalized), 80% of patients with a confirmed COVID-19 diagnosis were reported to continue having at least one symptom beyond two weeks following acute infection [13].…”
Section: Discussionmentioning
confidence: 66%
“…Numerous studies report intermediate prevalence rates between the above-mentioned ones [16,17]. The results clearly indicate that age, being female, poor general health, pre-existing health conditions, high viral load, obesity or being overweight and white ethnicity were associated with higher risk of long COVID in the majority of the studies [7,11,12,15].…”
Section: Discussionmentioning
confidence: 93%
“…A continuation of the Wuhan 6-month follow-up cohort study of hospitalized COVID-19 patients re-examined health status and other outcomes at 12 months. 34 The proportion of patients with at least one sequelae or symptom decreased from 68% at 6 months to 49% at 12 months. Fatigue and muscle weakness were the two most reported symptoms during both follow-up visits, and the proportion fell from 52% at 6 months to 20% at 12 months.…”
Section: Duration Of Symptomsmentioning
confidence: 95%
“…However, it provides similar estimates to the longest follow-up study to date (conducted in individuals in Wuhan, China), where 49% of individuals continued to have symptoms at 12 months, and this was at double the rate of age-sex-comorbidity matched controls. 34 COVID-19 in Ontario has been disproportionately concentrated in populations who are racialized, have lower socioeconomic status, are recent immigrants or essential workers. 67 Although our estimates are at the level of the province, it is likely that the burden and disability associated with the post COVID-19 condition will also be unequally distributed with greater prevalence in these groups.…”
Section: Expected Burden Of Post Covid-19 Condition In Ontariomentioning
confidence: 99%
“…In the second 12-month follow-up study ( 3 ), 1276 hospital survivors infected with COVID-19 were included to show the dynamic recovery of health outcomes within 12 months of symptom onset. The lung diffusion impairment and radiographic abnormalities persisted for up to 12 months in some patients.…”
mentioning
confidence: 99%