108. Comparison of Metal-on-Metal to Metal-on-Polyethylene Material Combinations for Lumbar Total Disc Arthroplasty Under Walking Conditions

An In Vitro Assessment of Wear Particulate Generated From NUBAC

“…However, regardless of design and material combination, these devices are expected to wear and produce particulate debris over the course of their expected lifetime. [1][2][3][4][5][6][7] Throughout its over 40-year history, the survivorship of total joint arthroplasty has been limited primarily by the generation of wear debris and its subsequent biologic sequela; aseptic loosening caused by a wear particle-mediated infl ammation and osteolytic cascade. 8,9 Therefore, given that the expected lifetime of a disc arthroplasty device can be 40 or more years, signifi cantly longer than that of a total hip or knee implant, wear and the accumulating wear particulate is of clinical concern, as this is considered a critical determinant of the devices' expected lifetime.…”