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Abstract

Fluorescent granular cells of the thymus lobule containing neurotransmitter monoamines express Ia antigen and S-100 protein, which attests to their macrophage origin; positive staining with aldehyde fuchsin points to secretion of peptide hormones by these cells. These facts and the absence of phagocytic activity allow to identify these cells as dendritic macrophages.

Effect of orchiectomy on structures of the thymus expressing major histocompatibility complex class II molecules

“…1). Morphological characteristics and localization of MHC-II + cells in the thymus were similar to those of luminescent granular cells, which belong to the population of dendrite macrophages [1].…”

Reaction of Thymic Monoamine-Containing Structures to Experimental Testectomy

“…The macrophagic nature of fluorescent granular cells of the thymus is proven [1,2,5]. Initiation of the immune response, particularly T-cell mediated response, largely depends on thymic macrophages.…”

Mesoporous Aerogel Microparticles Injected into the Abdominal Cavity of Mice Accumulate in Parathymic Lymph Nodes

“…In the case of mouse lymphatic tissue, next to the signal of the FSGM, the natural autofluorescence of the tissue was observed. The autofluorescence of the lymphatic tissues has been characterized in numerous previous studies [34,35]. Granular cells have a well-defined autofluorescence signal when applying the standard filter sets in the fluorescence microscope.…”