[15] Computational methods for transition state and inhibitor recognition

Braunheim, Benjamin B.; Schwartz, Steven D.

doi:10.1016/s0076-6879(99)08017-9

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Nucleoside Hydrolases2

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Cited by 6 publications

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“…It hydrolyzes all the natural nucleosides efficiently and has the highest specificity for inosine and uridine, hence the “IU” designation . In addition to TS analysis, , its mechanism has been studied through kinetic characterization, inhibition, and computational and structural studies. ,,,,− …”

Section: 6 Nucleoside Hydrolasesmentioning

confidence: 99%

“…308 In addition to TS analysis, 31,111 its mechanism has been studied through kinetic characterization, inhibition, and computational and structural studies. 65,187,224,225,[309][310][311][312][313][314][315][316][317][318][319][320] TS Analysis. The experimental KIEs were qualitatively similar to those for other N-glycoside hydrolysis reactions.…”

Section: Nucleoside Hydrolasesmentioning

confidence: 99%

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