[ 18 F]-Fluorodeoxyglucose Positron Emission Tomography in the Diagnosis, Treatment Stratification, and Monitoring of Patients with Retroperitoneal Fibrosis: A Prospective Clinical Study

Fernando, Archie; Pattison, James M.; Horsfield, Catherine; D’Cruz, David; Cook, Gary; O’Brien, Tim

doi:10.1016/j.eururo.2016.10.046

Cited by 37 publications

(25 citation statements)

References 30 publications

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“…The : 10.14302/issn.2641-5518.jcci-19 11 Although malignancy can be highly excluded by imaging methods and PET-CT, biopsy is often used to confirm the diagnosis. 12 In our case, the definitive diagnosis was obtained by biopsy after MRI and PET-CT imaging and PET-CT was helpful in the follow-up of the patient.…”

Section: Discussionmentioning

confidence: 69%

A Rare Cause of Acute Renal Failure: Retroperitoneal Fibrosis

Omer

Emre

Cihan

et al. 2019

JCCI

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Idiopathic retroperitoneal fibrosis also known as Ormonds disease is a rare disorder characterized by the development of fibrotic tissue in the retroperitoneum. The fibrotic tissue may compress ureters, leading to obstructive nephrouropathy and renal failure. A 58-year-old man with fatigue, loss of appetite and unable to urinate was admitted to our clinic. Because of the serum creatinine value of 5.3 mg/dl, urinary ultrasonography was performed and bilateral grade 3 hydronephrosis with moderate level urine in bladder was detected. Hydronephrosis did not regress by transurethral foley catheter and suspicious appearance in the retroperitoneal area was found in abdominal magnetic resonance imaging. Tru-cut biopsy result of the current lesion was finally reported as a connective tissue. Bilateral double j catheter insertion was performed and started to immunosuppression therapy with corticosteroid. Two months later, double j catheters were removed and hydronephrosis was not detected in follow-up. In this case report, we tried to explain that, retroperitoneal fibrosis should be considered in the differential diagnosis of postrenal acute renal failure, even in patients without a classic symptom such as pain. In addition, early surgical intervention should be avoided in such patients.

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Section: Discussionmentioning

confidence: 69%

A Rare Cause of Acute Renal Failure: Retroperitoneal Fibrosis

Omer

Emre

Cihan

et al. 2019

JCCI

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“…Our current policy is to offer ureterolysis to patients who are not stent‐free within 6 months of initiating medical treatment. In this regard, PET scanning may be useful in directing treatment decisions; if the RPF is non‐avid or weakly avid then patients are unlikely to respond to steroids and ureterolysis could be offered as a primary treatment . What would also be valuable in this regard would be a clear consensus from patients as to what they would consider successful management in RPF.…”

Section: Discussionmentioning

confidence: 99%

“…The aims have been to accelerate progress in our understanding of the disease and, in particular, to define the principal goals of investigation and treatment, to formulate a classification, to describe a coherent plan of initial investigation, and to understand the best long‐term management of ureteric obstruction. Progress has been made in optimizing initial management and has identified CT‐positron‐emission tomography (PET) as a useful tool in judging both the need for biopsy and whether the patient is likely to respond to steroids . In the present study, we examine the outcomes of ureterolysis and, in so doing, attempt to clarify the role of ureterolysis in the modern management of ureteric obstruction caused by RPF.…”

Section: Introductionmentioning

confidence: 99%

Contemporary role of ureterolysis in retroperitoneal fibrosis: treatment of last resort or first intent? An analysis of 50 cases

O’Brien

Fernando

2017

BJU International

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This study suggests that for patients with ureteric obstruction caused by RPF, contemporary ureterolysis performed by a high-volume specialist team can successfully render patients stent- or nephrostomy-free without compromising renal function. The results suggest that ureterolysis should be considered in all patients who present with ureteric obstruction caused by RPF that does not respond quickly to standard treatment.

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“…Although the fixation does not systematically cross morphological data visualized by the scanner and the MRI, nor the presence of a biological inflammatory syndrome. Functional imaging allows evaluation of the extent of systemic fibrosis, vascular and perivascular lesions [10,27,36].…”

Section: Discussionmentioning

confidence: 99%

Retroperitoneal Fibrosis: Case Series of 20 Patients

Said¹,

Ghoundale²,

Zakaria³

et al. 2017

SJPH

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Abstract:Retroperitoneal fibrosis (RPF) is a rare disease. The objective of this paper is to study the prevalence, clinical, biological and radiological aspects of the RPFand to specify its therapeutic modalities. This study provides descriptive evidence for a series of 20 patients with RPF. We conducted a retrospective study of cases of RPF diagnosed in the Urology and Internal Medicine departments of the Ibn Sina Military Hospital in Marrakech over a five-year period from July 2010 to December 2015. The positive diagnosis of RPF was retained either on the basis of a histological analysis from a biopsy fragment or, in the absence of histological evidence, by the detection on a scan of an infiltrate or "sleeve" Regular and homogeneous tissue density, perivascular topography, surrounding the abdominal aorta, more or less extended to the iliac vessels and able to take the contrast after injection. They were 15 men and 5 women with an average age of 53 years with extremes of 41 to 74 years. Almost all patients had mainly lumbar and abdominal pain. An inflammatory syndrome existed in all cases and renal insufficiency in 15 cases. Radiological investigations showed unilateral or bilateral hydronephrosis in 16 cases. RPF was idiopathic in 14 patients. Secondary forms were present in 6 patients (three atheromatous diseases, one gastric tumor, one case associated with Riedel's thyroiditis and one case of systemic fibrosis associating RPF, Riedel's thyroiditis and liver fibrosis). The treatment consisted of corticosteroids in 19 cases, surgery in 17 cases associated with corticosteroid therapy or even immunosuppressant in the case of steroid-dependence. Two deaths were observed in this series; one of these two patients had developed cervix carcinoma with pleural and peritoneal metastases after 5 years of immunosuppressive therapy. The second died due to the complications of his gastric neoplasm. The general characteristics of patients included are similar to the other series of the literature. The frequency of secondary forms seems to be underestimated, hence the value of a rigorous etiological investigation. The therapeutic strategy and the use of the cortisone saving treatments should be specified by randomized therapeutic trials. The prognosis is generally good; however, the possibility of recurrences, the incidence of which is greater during the first five years, requires prolonged clinical, biological and radiological monitoring.

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[ 18 F]-Fluorodeoxyglucose Positron Emission Tomography in the Diagnosis, Treatment Stratification, and Monitoring of Patients with Retroperitoneal Fibrosis: A Prospective Clinical Study

Cited by 37 publications

References 30 publications

A Rare Cause of Acute Renal Failure: Retroperitoneal Fibrosis

A Rare Cause of Acute Renal Failure: Retroperitoneal Fibrosis

Contemporary role of ureterolysis in retroperitoneal fibrosis: treatment of last resort or first intent? An analysis of 50 cases

Retroperitoneal Fibrosis: Case Series of 20 Patients

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