18F-FDG PET/CT Findings in a Patient With Primary Primitive Neuroectodermal Tumor of the Lung

Abstract

Primary primitive neuroectodermal tumor of the lung is an extremely rare and highly malignant neoplasm with a poor prognosis. A 49year-old man presented with a dry cough and slight pain in the left chest for nearly 1 month. 18 F-FDG PET/CT showed intense 18 F-FDG uptake of the left inferior lung tumor and hypermetabolic mediastinal lymph nodes. Histopathology revealed primitive neuroectodermal tumor after CT-guided transthoracic needle biopsy of the left inferior lung mass was performed.

A rare radiotherapy-sensitive primitive neuroectodermal tumor with APC gene amplification in an adult: a case report and literature review

“…However, positron emission tomography–computed tomography reveals high uptake of 18F-fluorodeoxyglucose in the tumor and regional lymph nodes, where the standardized uptake value is significantly higher than that in peripheral healthy tissues. 11 …”

“…However, positron emission tomographycomputed tomography reveals high uptake of 18F-fluorodeoxyglucose in the tumor and regional lymph nodes, where the standardized uptake value is significantly higher than that in peripheral healthy tissues. 11 The pathological features of PNET include highly aggressive behavior and small, round tumor cells originating from the central nervous system and sympathetic nervous system. 12 Differential diagnoses should include other small round cell tumors such as rhabdomyosarcoma, small cell lung cancer, lymphoma, and poorly differentiated synovial sarcoma.…”