18F-FDG PET/CT of Liver Lymphoepithelioma-like Carcinoma

Lee, Sin-Di; Chiu, Yu-Li; Wu, Chia-Shan; Peng, Nan‐Jing

doi:10.1097/rlu.0000000000000822

Cited by 6 publications

(3 citation statements)

References 10 publications

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“…All cases were 18 F-FDG-avid with wide-range of reported maximum standardized uptake values (SUVmax), ranging from SUVmax 1.7 to SUVmax 34.5 [6,7,9]. The previous observation concurs with our experience in these 7 patients, whom the LELC was metabolically active, with SUVmax 7.6 to SUVmax 14.5.…”

Section: Resultssupporting

confidence: 83%

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Utility of 18F-FDG PET/CT in the assessment of lymphoepithelioma-like carcinoma

Chan

Tsoi

Wong

et al. 2016

Nuclear Medicine Communications

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Lymphoepithelioma-like carcinoma (LELC) is a rare Epstein-Barr virus (EBV)-related disease, which commonly originates from the lung and is associated with more favourable treatment outcomes compared with other non-LELC thoracic carcinomas. Radiological assessment utilizing fluorine-18 fluorodeoxyglucose PET combined with computed tomography (F-FDG PET/CT) is important for initial disease staging to tailor the treatment strategy, evaluation of treatment response and detection of disease recurrence. The aim of this article was to highlight the utility of F-FDG PET/CT in different stages of disease evaluation of LELC. We reviewed seven patients with histologically proven LELC who underwent F-FDG PET/CT for disease evaluation. We described the F-FDG-avidity of LELC (ranged from maximum standardized uptake value 7.6 to maximum standardized uptake value 14.5 in our series) and highlighted the clinical values of F-FDG PET/CT in different stages of disease evaluation. F-FDG PET/CT enables accurate evaluation of the primary tumour, its relationship with the surrounding structures and accurate staging. It is also useful in treatment response assessment to monitor the efficacy of the treatment and to decide upon treatment strategy. Given the F-FDG-avidity of LELC, F-FDG PET/CT is advantageous in detecting tumour recurrence of LELC. LELC is a rare disease entity associated with EBV and is more prevalent in Asia, where EBV is endemic. LELC is an F-FDG-avid tumour. Although the features on F-FDG PET/CT are not specific, F-FDG PET/CT provides valuable information for disease management of LELC.

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Section: Resultssupporting

confidence: 83%

“…18 FDG-avidity of LELC There is few published data, limiting to case reports, in the 18 F-FDG-avidity of LELC [6][7][8][9][10].…”

Section: Resultsmentioning

confidence: 99%

Utility of 18F-FDG PET/CT in the assessment of lymphoepithelioma-like carcinoma

Chan

Tsoi

Wong

et al. 2016

Nuclear Medicine Communications

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“…Most of these tumors are also concomitant with Epstein-Barr virus (EBV) infection [3]. Primary LELC of the liver has recently been reported as well, although it is extremely rare [9].…”

Section: Introductionmentioning

confidence: 99%

Primary Pulmonary Lymphoepithelioma-like Carcinoma on FDG PET/CT

Aktaş

Can

Demir

et al. 2016

Nucl Med Mol Imaging

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A 69-year-old male smoker was referred to 18 Ff l u o r o d e o x y g l u c o s e ( F D G ) p o s i t r o n e m i s s i o n tomography-computed tomography (PET/CT) with the indication of a suspicious solitary pulmonary nodule. FDG PET/CT determined a 2.5 × 2-cm soft-tissue lesion (SUVmax, 16.2) with spiculated margins in the hilum of the right lung. A 1-cm diameter lymphadenopathy on the right hilum with an SUVmax of 3.2 was also determined. Transbronchial biopsy of the right hilar lymphadenopathy did not reveal any malignant features in histopathologic examination, and it was determined to be reactive. The patient underwent a right upper lobe segmentectomy, and the histopathologic evaluation revealed that the tumor was a primary lymphoepithelioma-like carcinoma (LELC) of the lung with negative Epstein-Barr virus (EBV) on in situ hybridization studies. In this case report, we mainly focus on the FDG avidity of this very rare kind of tumor comparatively with previous reports and possible explanations of discordancy in FDG avidity in relation to histopathologic characteristics.

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Clinical usefulness of F-18 FDG PET in lymphoepithelioma-like gastric carcinoma

Park

Lee

et al. 2017

European Journal of Radiology

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18F-FDG PET/CT of Liver Lymphoepithelioma-like Carcinoma

Cited by 6 publications

References 10 publications

Utility of 18F-FDG PET/CT in the assessment of lymphoepithelioma-like carcinoma

Utility of 18F-FDG PET/CT in the assessment of lymphoepithelioma-like carcinoma

Primary Pulmonary Lymphoepithelioma-like Carcinoma on FDG PET/CT

Clinical usefulness of F-18 FDG PET in lymphoepithelioma-like gastric carcinoma

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