18F-fluorodeoxyglucose positron emission tomography in monitoring of therapy effectiveness in large vessel vasculitides

Асланиди, И. П.; Manukova, V.A.; Мухортова, О. В.; Katunina, T.A.; Rudas, M.; Pozharov, I.V.; Novikov, Pavel; Мешков, А. Д.

doi:10.24022/1810-0694-2017-18-4-380-390

Cited by 2 publications

(2 citation statements)

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“…Thus, PET/CT results allow the detection of inflammatory processes even in a structurally unchanged vascular wall, i.e., in the early stages of LVV. This allows reducing the time to final diagnosis, initiating the treatment in a timely manner, and reducing the risk of complications [9,14,15]. According to multiple research results, 18F-FDG PET/CT is a non-invasive technique with a good accuracy for the early diagnosis of LVV: in the latest meta-analysis (n = 400), the pooled sensitivity and specificity were 75.9% (95% CI 68.7-82.1) and 93.0% (95% CI 88.9-96.0), respectively; with data limited to GCA-of 83.3% (95% CI 72.1-91.4) and 89.6% (95% CI 79.7-95.7), respectively [9].…”

Section: Discussionmentioning

confidence: 99%

Zoledronate-Induced Large Vessel Vasculitis Diagnosed by PET/CT

Shchekochikhin,

Vinogradskaya,

Bublik

et al. 2023

JVD

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Bisphosphonates remain a first-line treatment for osteoporosis. The most-widely used is zoledronate, which is well tolerated by most patients, but may rarely cause acute inflammatory reactions, which resemble those of large vessel vasculitis (LVV). We report a third case of LVV associated with zoledronic acid infusion, presenting with a 2-week history of fever up to 40 °C, flu-like symptoms, left jaw pain, myalgia, arthralgia, ankle stiffness in the morning, and intermittent claudication, diagnosed by the hybrid imaging modality 18F-FDG PET/CT with isolated lower extremity involvement and successfully treated with glucocorticoids.

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Section: Discussionmentioning

confidence: 99%

Zoledronate-Induced Large Vessel Vasculitis Diagnosed by PET/CT

Shchekochikhin,

Vinogradskaya,

Bublik

et al. 2023

JVD

View full text Add to dashboard Cite

show abstract

“…ПЭТ/КТ с 18F-ФДГ является современным неинвазивным методом радионуклидной визуализации, позволяющим одновременно оценивать метаболические и структурные изменения в органах и тканях. Наиболее широко ПЭТ/КТ с 18 F-ФДГ применяется в онкологии, однако в последние годы методика заняла важное место в ранней диагностике и оценке эффективности лечения различных воспалительных процессов [9]. Известно, что 18 F-ФДГ интенсивно накапливается клетками воспаления -активированными гранулоцитами, лимфоцитами и макрофагами, что позволяет использовать данный радиофармпрепарат для диагностики и оценки распространенности воспалительных процессов различной этиологии.…”

Section: Discussionunclassified