18F-Fluorodeoxyglucose Uptake in Abdominal Aortic Aneurysms: A Useful Biomarker of AAA Rupture Risk

Aortic wall inflammation: a more accurate predictor of aneurysm expansion and aneurysm rupture risk than aortic diameter?

“…Inflammation plays a key role in the development of AAAs (5). Furthermore, increased 18F-fluorodeoxyglucose (18F-FDG) uptake that is detected by positron emission tomography (PET) in AAAs has been demonstrated to be associated with inflammation, aortic wall instability and an increased AAA rupture risk (6,7). The MA 3 RS study therefore extends the results of previous studies and shows that USPIO-enhanced MRI predicts the rate of AAA expansion, as well as the risk of AAA rupture and AAA repair.…”