195. Some substituted 1,3,5-triazines

Abstract

The preparation and properties of some substituted 1,3,5-triazines are described. Replacement of 1, 2, or 3 of the chloro-groups of cyanuric chloride by bromo-groups during the preparation of monoalkyldichlorotriazine from cyanuric chloride and alkylmagnesium bromide has been demonstrated. Differences in the ease of transesterification of some esters of cyanuric acid are described.

A General and Selective Copper‐Catalyzed Cross‐Coupling of Tertiary Grignard Reagents with Azacyclic Electrophiles

“…Limiting the amount of the Grignard reagent and lowering of the reaction temperature led to selective monoalkylations (Table 1, entries 6, 9, and 10). The latter conditions may be compared to those of a noncatalyzed alkylation (2 c!3 c: 112 8C, 3.5 h, 24 % yield) [24] to illustrate the impressive catalytic acceleration by copper(I). Trisubstitution was achieved in the case of cyanuric chloride (2 c) by performing consecutive alkylations in one pot (Table 1, entry 12).…”