2,4,4a,5,6,7,9,9a-Octahydrofuro[2,3-f]indolizin-7-one

Abstract

Key indicatorsSingle-crystal X-ray study T = 183 K Mean '(C±C) = 0.002 A Ê R factor = 0.041 wR factor = 0.115 Data-to-parameter ratio = 15.7For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e. ExperimentalThe title compound was prepared by diastereoselective reduction of the furan ring of starting (4R,4aS)-4-hydroxy-4,4a,5,6,7,9-hexahydro[2,3-f]indolizin-7-one (Szemes et al., 1998) to the 2,5-dihydro-

(3aR,4R,4aS,9aR)-4-Hydroxyperhydrofuro[2,3-f]indolizin-7(2H)-one

“…1. The bond lengths and angles in the molecule (Table 1) are comparable with those in a related structure (Vrá bel et al, 2004). The central sixmembered ring is not planar and adopts a chair conformation (Cremer & Pople, 1975).…”

1,1′-[4-(5-Bromo-2-furyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-diyl]diethanone

“…The bromo substituent lies above the C4-H4 bond in a synperiplanar orientation, and not over the centre of the boat. The bond lengths and angles in the molecule are comparable with those in a related structure (Vrá bel, et al, 2004). Intermolecular N-HÁ Á ÁO hydrogen bonds link the molecules of (I) into extended chains, which run parallel to the b axis ( Fig.…”