2-Amino-3,4-dimethylimidazo[4,5-f]quinoline is not detectable in commercial instant and roasted coffees

Gross, Gian A.; Wolleb, U.

doi:10.1021/jf00012a026

Cited by 4 publications

(3 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The content of MeIQ was estimated to be 0.16-1.5 ng/lO g coffee beans. Gross and Wolleb [1991] failed to confirm the finding of MeIQ in commercial instant coffee or roasted coffee samples.…”

Section: Discussionmentioning

confidence: 87%

Characterization of mutagenic activity in instant hot beverage powders

Johansson

Knize

Jägerstad

et al. 1995

Environ and Mol Mutagen

View full text Add to dashboard Cite

Extracts of several grain-based coffee-substitute blends and instant coffees were mutagenic in the Ames/Salmonella test using TA98, YG1024, and YG1029 with metabolic activation. The beverage powders induced 150 to 500 TA98 and 1,150 to 4,050 YG1024 revertant colonies/g, respectively. Increased sensitivity was achieved using strain YG1024. No mutagenic activity was found in instant hot cocoa products. The mutagenic activity in the beverage powders was shown to be stable to heat and the products varied in resistance to acid nitrite treatment. Differential bacterial strain specificity, and a requirement for metabolic activation suggest that aromatic amines are present. Characterization of the mutagenic activity, using HPLC and the Ames test of the collected fractions, showed the coffee-substitute blends and instant coffees contain several mutagenic compounds. Known heterocyclic amines are not responsible for the major part of the mutagenic activity. The main mutagenic activity in grain-based coffee-substitute blends and instant coffees is due to several unidentified compounds, which are most likely aromatic amines.

show abstract

Section: Discussionmentioning

confidence: 87%

Characterization of mutagenic activity in instant hot beverage powders

Johansson

Knize

Jägerstad

et al. 1995

Environ and Mol Mutagen

View full text Add to dashboard Cite

show abstract

“…More than twenty HAs have been isolated from several food samples and model systems, and some of their structures determined. Although suspected [4], the presence of HAs on roasted coffee was not yet confirmed [5,6].…”

Section: Introductionmentioning

confidence: 93%

“…Two complementary cleaning methods were tested. On the first, and according with Gross and Grüter [5], the initial aqueous coffee extract was adjusted to pH 7.5 and mixed with preconditioned XAD-2 (10 g). After being washed with water (100 ml), elution was performed with methanol (30 ml) and methanol-acetone (1:1, v/v; 20 ml).…”

Section: Applicationmentioning

confidence: 99%