(2-Oxo-2H-benzo[h]chromen-4-yl)methyl morpholine-4-carbodithioate

Abstract

In the title compound, C19H17NO3S2, the morpholine ring is in a chair conformation. In the coumarin ring system, the dihedral angle between the benzene and pyran rings is 3.9 (1)°. In the crystal, weak C—H⋯O inter­actions link the mol­ecules into corrugated layers parallel to (102). The crystal packing also exhibits π–π inter­actions, with distances of 3.644 (1) and 3.677 (1) Å between the centroids of the benzene rings of neighbouring mol­ecules.

Crystal structure of (7-fluoro-2-oxo-2H-chromen-4-yl)methyl morpholine-4-carbodithioate

“…For applications of coumarins, see: Starčević et al (2011); Lodeiro et al (2010); Danko et al (2011). For a related structure and further synthetic details, see: Kant et al (2012).…”

(6-Methoxy-2-oxo-2H-chromen-4-yl)methyl pyrrolidine-1-carbodithioate

“…For a related structure and background to the properties of coumarins, see: Kant et al (2012). For further synthetic details, see: Shastri et al (2004); Vasilliev et al (2000).…”

“…In continuation of our interest on crystal structures of coumarin derivatives (Kant et al, 2012), we now report the crystal structure of the title compound.…”

(5,7-Dimethyl-2-oxo-2H-chromen-4-yl)methyl pyrrolidine-1-carbodithioate

“…For biological properties of coumarins, see: Adavi et al (2004); Laurin et al (1999); Kulkarni et al (2006). For related structures, see: Kumar et al (2012); Kant et al (2012). For synthetic details, see: Shastri et al (2004); Vasilliev & Polackov (2000).…”

“…In our present work, we have been able to link a dithiocarbamate group at the C-4 methylene carbon and it was deemed of considerable interest to study the effect of this group on the total solid state conformation of the molecule. The synthesized compound was screened for antimicrobial, antidiabetic, DNA binding and DNA cleavage studies.In continuation of our interest in the crystal structures of coumarin derivatives (Kumar et al, 2012;Kant et al, 2012), we report here the crystal structure of the title compound.…”