2-Picolylamino(diphenylphosphinoselenoic)amide supported zinc complexes: Efficient catalyst for insertion of N–H bond into carbodiimides, isocyanates, and isothiocyanate

A binuclear aluminium complex as a single competent catalyst for efficient synthesis of urea, biuret, isourea, isothiourea, phosphorylguanidine, and quinazolinones

“…[5][6][7][8][9][10][11][12] In contrast to the signicantly developed catalytic hydroamination of alkynes, alkenes, and carbodiimides to form C-N bonds, [13][14][15] catalytic hydroamination of isocyanates, leading to urea derivatives, have been explored only by some group 2, titanium, zinc, actinide complexes, etc. [16][17][18][19][20][21][22] The urea derivatives are useful across a range of biological systems, pharmaceuticals, agrochemicals, synthetic chemistry, supramolecular chemistry, and materials chemistry. [23][24][25][26][27][28][29][30][31] Moreover, the synthesis of derivatives containing multiple urea moieties within one molecule, such as biuret and triuret derivatives from monourea, is quite challenging since the nucleophilic nature of urea compared to secondary amines is considerably less.…”

Amide-Assisted Rearrangement of Hydroxyarylformimidoyl Chloride to Diarylurea

“…Given the medicinal and biological properties of N, N -disubstituted urea, syntheticorganic chemists and medicinal chemists have shown considerable interest in the development of efficient methodologies for the synthesis of this structure. The traditional methods of synthesizing urea involve the condensation reaction between an amine and active carbonyl compounds, such as isocyanate [19][20][21][22], chloroformate [23], and carbonyl di-imidazole [24,25] (Scheme 1a). Also, the Curtius rearrangement provides an effective method for preparing urea from an arylformyl chloride substrate (Scheme 1b) [26][27][28].…”

Copper ferrite nanoparticles: an effective and recoverable nanomagnetic catalyst for the synthesis of N , N ′, N ″‐trisubstituted guanidines from the addition reaction of anilines to carbodiimide

“…Generally, proceeding this synthetic method requires a metal-catalised process which mainly involves the use of transition-metal catalysts. Accordingly, numerous reports have been presented about the synthesis of guanidine derivatives through the reaction of aromatic and aliphatic amines with carbodiimides (carbodiimide guanidylation) by means of metal-based catalysis [22][23][24][25][26].…”