No abstract

O n e -P o t R e d u c t i v e A l k y l a t i o n o f P r i m a r y a n d S e c o n d a r y A m i n e s Abstract: A simple and convenient procedure for the reductive alkylation of primary and secondary amines and N,N-dimethylation of amino acids is described using sodium borohydride as a reducing agent in 2,2,2-trifluoroethanol without use of a catalyst or any other additive. The solvent can be readily recovered from reaction products in excellent purity for direct reuse.

A carbon-paste electrode modified with 2,7-bis(ferrocenyl ethyl)fluoren-9-one and carbon nanotubes was used for the sensitive voltammetric determination of levodopa (LD). The electrochemical response characteristics of the modified electrode toward LD, uric acid (UA) and folic acid (FA) were investigated. The results showed an efficient catalytic activity of the electrode for the electrooxidation of LD, which leads to lowering its overpotential by more than 320 mV. The modified electrode exhibits an efficient electron mediating behavior together with well-separated oxidation peaks for LD, UA and FA. Also, the modified electrode was used for determination of LD in some real samples.

No abstract

A simple and efficient method for the coupling of aryl iodides with aliphatic alcohols and phenols that does not require the use of alkoxide bases is described. This C-O bond forming procedure shows that the combination of air stable CuI and 1,10-phenanthroline in the presence of KF/Al 2 O 3 comprises an extremely efficient and general catalyst system for the etherification of aryl iodides. Different functionalized aryl iodides were coupled with alcohols and phenols using this method.