An ultra‐low quiescent current tri‐mode DC–DC boost converter is proposed in this paper, which can efficiently handle loads from 1 μA to 300 mA, providing 5‐V output from 3 to 4.2‐V input. Hysteresis current mode control is adopted to realize seamless mode switching between continuous conduction mode (CCM) and discontinuous conduction mode (DCM). In order to deal with the light load situation, this paper proposes a quasi burst mode (QBM). In this mode, most of the modules are turned off and only the QBM controller, low‐power current bias and sample and hold circuit are retained, which significantly reduces the static current of the converter, and thus improves the light load efficiency. Meanwhile, the average current of error amplifier and comparator are reduced significantly by dynamic biasing. Finally, the efficiency of the converter is greatly improved and kept at a reasonable output ripple. The proposed converter is implemented in a 0.13‐μm BCD process design and manufacturing. The test results show that the quiescent current of the converter is only 780 nA, which can achieve a peak efficiency of 95.6%, and ensure that the efficiency is maintained above 80% in the load range of 10 μA to 300 mA.