U nlike in adults, about whom much has been learned with respect to the pathogenesis of atherogenic cardiovascular disease (CVD), there remains a relative lack of basic and clinical data on adolescents. Recent data have begun to suggest, however, that the origins of CVD can be traced back to childhood (1,2). The risk for future development of CVD in children with abnormal values for cardiovascular risk factors (RF) and metabolic syndrome (MetS) is high, and early indicators for CVD, such as carotid artery intimal-media thickness and atherosclerotic plaques, have been shown to develop in childhood (3,4).Although the details of the transition from CVD RF in adolescents to CVD in adults are not clear, compelling evidence indicates that the pathological processes associated with CVD can be tracked from adolescence to adulthood (5,6). The National Health and Nutrition Examination Survey (NHANES) reported a high prevalence of CVD RF among adolescents, with about half of the OBJECtiVE: The authors previously reported that adult South Asian immigrants to Canada have an increased risk of cardiovascular disease (CVD) compared to their European and Chinese counterparts. It is unknown whether these ethnic differences also exist among adolescents, and whether they are related to diet and lifestyle. The objective of the present study was to assess the prevalence of CVD risk factors among apparently healthy adolescents in the three largest ethnic population groups in Canada (European, South Asian and Chinese). MEtHODS: A cross-sectional study among secondary school students in the Greater Toronto Area was undertaken. A total of 203 adolescents from 62 GTA secondary schools were recruited (48% Europeans, 35% Chinese and 18% South Asians) with a mean age of 17.3±1 years; 72% were female. RESUltS: Similar to adults, South Asian adolescents have increased rates of CVD risk factors compared with their European and Chinese peers, including higher prevalence of low high-density lipoprotein levels (P=0.001), high triglycerides (P=0.006) and high triglyceride/ high-density lipoprotein levels (P<0.001), despite no significant differences in dietary intake among the ethnic groups. European adolescents had higher rates of self-reported intensity of physical activity (P=0.002) than their Chinese or South Asian peers. COnClUSiOnS: Similar to adult data, South Asian adolescents have comparably higher rates of CVD risk factors compared with their European or Chinese peers, which could partly be attributed to lower physical activity in South Asian adolescents. Whether the findings in these selected samples of healthy adolescents can be generalized to their respective populations requires further validation. RÉSUltAtS : Tout comme les adultes, les adolescents sud-asiatiques présentent un taux plus élevé de facteurs de risque de MCV que leurs homologues européens et chinois, y compris une plus forte prévalence de lipoprotéines de haute densité (HDL) faibles (P=0,001), de triglycérides (TG) élevés (P=0,006), et de ratio TG/HDL élevé (P<0,001), ma...