201Tl for the differential diagnosis of cold thyroid nodules

Palermo, F.; Cadel, A; Bordignon, Gianfranco; Bruniera, Federico; Caldato, L.; Siega, Maurizio Della; Lazzarini, Mario; Mareso, Antonio

doi:10.1007/bf02881823

Cited by 3 publications

(1 citation statement)

References 2 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Таллий-201, в отличие от радиоцезия, имеет более оптимальные для сцинтиграфии физические характеристики (период полураспада 73 ч, основной энергический пик в диапазоне от 69 до 81 кэВ). Клинический анализ результатов обследования пациентов с обоими РФП показал некоторое преимущество хлорида таллия-201 перед хлоридом цезия-131 за счет отсутствия ложноположительных находок при подостром тиреоидите [28].…”

Section: метаболический скрининг узлов щитовидной железыunclassified

Scintigraphy in Thyroid Nodular Pathology

Mironov

Сергиенко

2022

Vestn. rentgenol. radiol.

View full text Add to dashboard Cite

Thyroid scintigraphy is a method that formed more than 60 years ago and retains its importance for the diagnosis and assessment of the risk of nodular malignancy. The review examines the use of the scintigraphic method in functional and metabolic assessment of nodular goiter. Prerequisites for functional thyroid nodes screening with short-lived 99mTc-pertechnetate are outlined. Information is provided on the principles of its preparation and pharmacokinetics, as well as variants of the thyroid nodes functional activity, their possible malignant potential and indications for metabolic screening. The characteristic of metabolic activity allows to assess the risk of functionally “cold” thyroid nodes malignancy. The main stages of the use of nonspecific tumorotropic radiopharmaceuticals, the mechanism of their accumulation and metabolism in the thyroid tumors, the possibilities of the differential diagnosis of various types of nodular formations are presented. Modern views on the diagnostic capabilities of two-phase scintigraphy with 99mTс-methylisobutylisonitrile are reflected taking into account the relationship of radiopharmaceuticals accumulation with factors of proliferative activity and ultrastructural cell types, a variant of oncocytic pathology and multidrug-resistant protein expression.

show abstract

Section: метаболический скрининг узлов щитовидной железыunclassified

Scintigraphy in Thyroid Nodular Pathology

Mironov

Сергиенко

2022

Vestn. rentgenol. radiol.

View full text Add to dashboard Cite

show abstract

Management of thyroid nodules. II: Scanning techniques, thyroid suppressive therapy, and fine needle aspiration

1981

View full text Add to dashboard Cite

For the differentiation of benign from malignant thyroidal disease, ultrasound displays anatomic but not histologic features. Other visualization techniques can be used including isotope scanning (radioiodine, 99m technetium, 241 americium fluorescence, 131 cesium, 67 gallium, 75 selenomethionine, 201 thallium, 32 phosphorus, 99m Tc-bleomycin, 197 mercury, 133 xenon), thermography, x-ray techniques (plain films, computed tomographic scan, xeroradiography, chest x-ray barium swallow, lymphography, angiography), and thyroid hormone suppression. Needle biopsy can be done by core biopsy (Vim-Silverman and drill biopsy), large needle biopsy for histologic processing and fine needle aspiration for cytologic interpretation. The latter is the safest, most reliable, and most cost-effective technique currently available to differentiate between benign and malignant thyroidal disease and has great promise for the future.

show abstract