214 Airway reactivity in Cystic Fibrosis

Ciofu, C; Cernatescu, I.; Ciofu, Elena

doi:10.1016/s1569-1993(06)80196-7

Cited by 3 publications

(6 citation statements)

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“…Disorders of hemostasis can be classified into vascular, platelet and coagulation factors defects. Each one of the previously mentioned anomalies can be hereditary or acquired [1–3,7].…”

Section: Case Reportmentioning

confidence: 99%

“…The possible causes of fat malabsorption can be grouped in hepatobiliary disorders (such as hepatitis, cirrhosis, cholestatic syndromes etc. ), pancreatic and intestinal diseases, respectively [1–3].…”

Section: Case Reportmentioning

confidence: 99%

“…Exocrine pancreatic insufficiency is one of the maldigestion-malabsorption syndromes, thus being associated with poor digestion and, subsequently with diminished intestinal absorption of one or more dietary nutrients. Exocrine pancreatic insufficiency is determined by various pancreatic enzyme deficiencies causing an alteration at the level of the intestinal lumen which results in chronic diarrhea and steatorrhea, that are in turn responsible for the development of multiple nutrient deficiencies, including fats, proteins, carbohydrates, vitamins (especially fat-soluble A, D, E, K) and electrolytes, with specific clinical consequences [1–3]. However, fat maldigestion-malabsorption seems to be the most important physiopathological process, which explains why steatorrhea is the main clinical symptom of exocrine pancreatic insufficiency.…”

Section: Introductionmentioning

confidence: 99%

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Bruising as the first sign of exocrine pancreatic insufficiency

Szabo

Man

Șerban

et al. 2019

Medicine and Pharmacy Reports

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Exocrine pancreatic insufficiency is an important cause of chronic malnutrition, secondary to maldigestion-malabsorption, which can be caused in children especially by cystic fibrosis, but also by other much rarer diseases. The case of a 6 months and 3 weeks old male pediatric patient is reported, who was admitted to the clinic for head and forearms bruising. Laboratory findings identified vitamin K deficiency as the cause of the cutaneous hemorrhagic syndrome. Further investigations revealed association of steatorrhea (which is a marker of fat malabsorption), iron-deficiency anemia and hypovitaminosis D, which had been produced by nutritional deficiencies caused by malabsorption syndrome. From the numerous disorders that could be associated with pancreatic insufficiency in children, the following conditions had been excluded: cystic fibrosis (mucoviscidosis), cow`s milk protein intolerance, gluten-sensitive enteropathy (coeliac disease), Shwachman-Diamond syndrome, abetalipoproteinemia, etc. Based upon decreased levels of stool pancreatic elastase in repeated measurements, together with low serum lipase, the final diagnosis of exocrine pancreatic insufficiency was established. Treatment of this case consisted mainly in pancreatic enzyme replacement therapy, but also oral iron supplementation and dietary supplements with fat-soluble vitamins (A, D, E, K). The outcome was favorable, characterized by normalization of intestinal passage, ascending growth curve and normalization of the majority of laboratory tests values that were modified between the time of patient admission to our clinic and initiation of specific therapy (serum level of vitamin K, vitamin D and lipase, coagulation profile, hemoglobin and red blood cell indexes), as well as higher value of fecal pancreatic elastase.

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“…Disorders of hemostasis can be classified into vascular, platelet and coagulation factors defects. Each one of the previously mentioned anomalies can be hereditary or acquired [1–3,7].…”

Section: Case Reportmentioning

confidence: 99%

Section: Case Reportmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Bruising as the first sign of exocrine pancreatic insufficiency

Szabo

Man

Șerban

et al. 2019

Medicine and Pharmacy Reports

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“…Among adolescents, acute intoxications caused by drugs as well as intoxications caused by toxic substances make up an important chapter of emergency pediatric pathology because of the diagnostic challenges and also of the vital risk that is emerging from these (1).…”

Section: Introductionmentioning

confidence: 99%

The Spectrum of Intoxication Among Adolescents

Iorga,

Mihai,

Chisnoiu

et al. 2022

ARS Medica Tomitana

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Among adolescents, acute intoxications caused by drugs as well as intoxications caused by toxic substances make up an important chapter of emergency pediatric pathology. We conducted a retrospective study carried out for a period of 1 year, 2021–2022, which included a number of 37 patients, admitted in the Pediatric Clinic of the County Clinical Hospital “Sfântul Apostol Andrei” Constanța. Out of the total of admissions during a 12 months period, 0,5% consisted in acute intoxications in adolescents. There is a higher tendency for substance intoxication in females (65,5% of total cases). There is a higher tendency for adolescents with suicide ideation to use substances in order to end their life because of multiple risk factors, mental health disorders putting them at a higher risk to attempt suicide. Alcohol is widely used.

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“…The moment when complementary feeding is introduced depends on the child's age, the previous diet and nutrition status. There have been known important debates referring to the optimum moment of complementary feeding, discussing the advantages/disadvantages of early complementary feeding (at ~ 3 months) (6,7).…”

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confidence: 99%

Untitled

2015

Ro J Pediatr

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Nutrition epitomizes the whole range of physiological processes of absorbtion and decomposition of food in the body, as required for growth and development. The debates on the feeding trends are topical, a large number of scientifi c boards and international committees fully concentrate on the impact of correct feeding on growth and harmonious development, starting even from intrauterine life. The progressive introduction of half solid and solid food in the infant's diet after 4-6 months, gradually replacing the milk meals previously administered is known as diversifi ed (complementary) feeding. The latest recommendations of the ESPGHAN Committee (European Society for Pediatric Gastroenterology, Hepatology and Nutrition) regarding the moment of switching from an exclusively milk diet to a diet which includes other foods is included in the period of time between week 17 and 26. The compliance and the collaboration of the family with the doctors are of paramount importance. Considering the present day open access to a lot of information, sometimes without any scientifi c basis, we believe it is opportune to review briefl y the main aspects of the complementary feeding according to the recommendations in the fi eld.

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214 Airway reactivity in Cystic Fibrosis

Cited by 3 publications

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Bruising as the first sign of exocrine pancreatic insufficiency

Bruising as the first sign of exocrine pancreatic insufficiency

The Spectrum of Intoxication Among Adolescents

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