22‐2: Smart Pharmaceutical Packaging with E‐Paper Display for improved Patient Compliance

Abstract

Today's packaging for pharmaceutics provides no information about individual medicine intake neither remind when forgotten or alert when medicine runs empty. We developed three smart packages for those examples with graphics e-paper driven by a microcontroller with Bluetooth LE and a smartphone app. The evaluation with subjects was very positive.

Enhancing Pharmaceutical Packaging through a Technology Ecosystem to Facilitate the Reuse of Medicines and Reduce Medicinal Waste

“…QR (quick response) codes combined with SMS (short message service) can be an alternative but a smartphone is required and a predefined standard for QR codes becomes necessary [67]. A dynamic display on the pharmaceutical packaging showing all details of the medicines will be a better way to show all updated information to the patients, and an e-ink (electronic ink) display will be a good low-power (zero power when the display content is stable) method acting as a real-time visual indicator on the pharmaceutical packaging [68]. The flexible e-ink display not only shows the updated information of the medicine inside the packaging, a microprocessor driving the display can also report a real-time quality status according to the sensing results.…”

“…Quality (i) storage temperature monitoring: passive TTI [43][44][45] (ii) storage temperature monitoring: active TTI with digital interfaces [46] (iii) thin-film technology: printed sensors and RFID tags [47][48][49][50] (iv) thin-film technology: hybrid printed circuits [51,52] (v) thin-film technology: nanotechnology [53][54][55] (vi) contamination detection: PT/GC/MS methodology [56,57] (vii) contamination detection: computer vision [58] (viii) contamination detection: tamper-evident check [59,60] (ix) motion detection: wearable sensors [63,64] (x) expiry date detection: visual inspection [66] (xi) expiry date detection: QR codes and smartphones [67] (xii) on packaging display: e-ink displays [68] and EC displays [69,70] Safety (i) tamper-proof: tamper-evident and tamper-resistance on packaging [71][72][73]75] (ii) tamper-proof: tamper-evident for transportation [74] (iii) tamper-proof: implementation during production [23,76] (iv) tamper-proof: built-in digital interfaces [77,78] (v) anti-counterfeit: overt/covert indications [80][81][82] (vi) anti-counterfeit: packaging materials inspection [83][84][85] (vii) anti-co...…”

Medication Adherence: A Review and Lessons for Developing Countries

“…Smart prescription [35] Smart Assist: a smartphone intervention based on augmented reality for propagating drug adherence in patients with special needs and the elderly. The application is user-friendly and makes use of the smartphone camera in detecting medications.…”

48.1: Invited Paper: Applications for Bistable Electronic Paper Display without battery

“…This could make the product cost down and thinner. This technology could be used in name card, luggage label, Building instructions and so on [1,2].…”