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Belyakov, V.V.; Krakovskii, B. D.; Popov, O. M.; Step, G. Kh.; Udut, V. N.

doi:10.1023/a:1019692103797

Cited by 9 publications

(4 citation statements)

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“…To quantify polysaccharides, fructosides and fructosans a technique for burdock roots of State Pharmacopoeia XIV of Russia and Inulahelenium by Belyakov, adapted for seeds was used [30,31].…”

Section: Extraction Of Fructus Samples For Examination By Uv Spectros...mentioning

confidence: 99%

Chromatographic and Spectral Study of Arctium Lappa and Arctium Tomentosum Fructus Cultivated in Altai

Kolomiets,

Boev,

Zhalnina

et al. 2024

JCPRM

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Burdock is an ingredient of official and traditional medicines in different countries, its roots are used for food, biologically active additives, functional nutrition products, fertilizers, etc. A great demand led to the situation when many countries including Russia began the plant’s cultivation. Despite that, the aboveground parts of the plant including its fructus still remain expendable. At the moment, burdock fructus are officially used only in China and Japan. In Russia they are not used and studies of their chemical composition and pharmacological properties are scarce. The research showed that fructus of Arctium lappa and A. tomentosum cultivated in Altai using by traditional way of growing, and new of agrotechnics of cultivation contain lignans, hydroxycinamic acid, fatty acids and their derivatives, polysaccharides and anthocyanin’s. The use of a new cultivation technology increased the content of lignans and other BAS by 10–25%. Hydroxycinamic acid is one of the dominant substances in fructus by content, therefore it is possible to standardize raw material according to this parameter. The presence of methyl cis-9, cis-15-octadecadienoate and 11-Eicosenoic acid methyl ester in fructushas been discovered for the first time. Ethyl linoleate and methylfolate or methyl cis-9-octadecenoate are found to be dominant components of fatty acids and their derivatives. Additional studies of chemical composition, pharmacological properties, clinical approbation are needed to obtain evidence of the efficiency of burdock fructus utilization for clinical purposes and prevention.

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Section: Extraction Of Fructus Samples For Examination By Uv Spectros...mentioning

confidence: 99%

Chromatographic and Spectral Study of Arctium Lappa and Arctium Tomentosum Fructus Cultivated in Altai

Kolomiets,

Boev,

Zhalnina

et al. 2024

JCPRM

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“…H 2 is the main refrigerant in most of the traditional H 2 liquefaction processes. Its application includes drawbacks such as the inability to decrease the temperature below the H 2 boiling point, the high SEC of compressors, and high penetration in equipment structure due to low molecular mass and low system efficiency. , Helium refrigerant and Ne gas were proposed to solve the problems caused by H 2 ; the larger molecular mass of helium significantly reduces the power consumption, and its penetration decreases due to the larger molecules of helium. , Figure depicts the various temperature ranges of low-boiling fluids used as refrigerants for H 2 liquefaction. H 2 and helium refrigerants are the most suitable options for H 2 liquefaction.…”

Section: Description Of Liquid Hydrogen Technologiesmentioning

confidence: 99%

“… 165 , 194 Helium refrigerant and Ne gas were proposed to solve the problems caused by H 2 ; the larger molecular mass of helium significantly reduces the power consumption, and its penetration decreases due to the larger molecules of helium. 78 , 195 Figure 10 depicts the various temperature ranges of low-boiling fluids used as refrigerants for H 2 liquefaction. H 2 and helium refrigerants are the most suitable options for H 2 liquefaction.…”

Section: Description Of Liquid Hydrogen Technologiesmentioning

confidence: 99%

Strategies To Improve the Performance of Hydrogen Storage Systems by Liquefaction Methods: A Comprehensive Review

et al. 2023

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The main challenges of liquid hydrogen (H2) storage as one of the most promising techniques for large-scale transport and long-term storage include its high specific energy consumption (SEC), low exergy efficiency, high total expenses, and boil-off gas losses. This article reviews different approaches to improving H2 liquefaction methods, including the implementation of absorption cooling cycles (ACCs), ejector cooling units, liquid nitrogen/liquid natural gas (LNG)/liquid air cold energy recovery, cascade liquefaction processes, mixed refrigerant systems, integration with other structures, optimization algorithms, combined with renewable energy sources, and the pinch strategy. This review discusses the economic, safety, and environmental aspects of various improvement techniques for H2 liquefaction systems in more detail. Standards and codes for H2 liquefaction technologies are presented, and the current status and future potentials of H2 liquefaction processes are investigated. The cost-efficient H2 liquefaction systems are those with higher production rates (>100 tonne/day), higher efficiency (>40%), lower SEC (<6 kWh/kgLH2), and lower investment costs (1–2 $/kgLH2). Increasing the stages in the conversion of ortho- to para-H2 lowers the SEC and increases the investment costs. Moreover, using low-temperature waste heat from various industries and renewable energy in the ACC for precooling is significantly more efficient than electricity generation in power generation cycles to be utilized in H2 liquefaction cycles. In addition, the substitution of LNG cold recovery for the precooling cycle is associated with the lower SEC and cost compared to its combination with the precooling cycle.

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“…The production technology of alantolactone reference sample (3) has been developed which includes the following stages: extraction of essential oil from rhizomes and roots of Inula helenium L. by distillation with water vapor with simultaneous extraction in chloroform; isolation of the sum of sesquiterpene lactones by column chromatography on silica gel (eluent-mixture petroleum ether-ethyl acetate 9:1) [8].…”

Section: Introductionmentioning

confidence: 99%

Production Technologies of Pharmacologically Active Sesquiterpene Lactones

Kishkentayeva¹

2018

Eurasian Chem. Tech. J.

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Sesquiterpene lactones form a large group belonging to natural terpenoids series, generally found in plants of Asteraceae family and exhibiting anti-tumor, antiviral, immunostimulant, antifungal, antimicrobial, anti-inflammatory, antimutagenic, growth stimulating, antifeedant effects. Therefore, search for new compounds with a broad spectrum of pharmacological activity in this series provides the opportunities for effective and conceptually new drug design. The basis of the technology for the isolation of sesquiterpene lactones is the extraction of raw materials with various organic solvents, followed by chromatographic purification. Sesquiterpene lactones have no common properties that can be used in their isolation. Some of them are well soluble in non – polar solvents, others-only in polar, in this regard, the methods of isolation of sesquiterpene lactones are diverse. The greatest number of sesquiterpene lactones is isolated from leaves and flowers, slightly less – from roots and bark. Therefore, the development of methods for their isolation is associated with the selection of solvents and optimization of the extraction mode. Unfortunately, very few medicines based on sesquiterpene lactones are produced by the pharmaceutical companies today. Complexity of introduction of pharmacologically active sesquiterpene lactones technology into pharmaceutical production is in imperfection of their isolation methods from plant raw material, their purification and separation from obtained extracts. Production technologies of the patented medicines "Santonin", "Alanton" on the basis of sesquiterpene lactones are multiphase, labor-intensive, implying the use of many toxic organic solvents which is against the international GMP standards.

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Cited by 9 publications

References 0 publications

Chromatographic and Spectral Study of Arctium Lappa and Arctium Tomentosum Fructus Cultivated in Altai

Chromatographic and Spectral Study of Arctium Lappa and Arctium Tomentosum Fructus Cultivated in Altai

Strategies To Improve the Performance of Hydrogen Storage Systems by Liquefaction Methods: A Comprehensive Review

Production Technologies of Pharmacologically Active Sesquiterpene Lactones

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