289 oral LIMITED-VOLUME PERIOPERATIVE HDR BRACHYTHERAPY AS A SUBSTITUTE FOR WIDE-FIELD EBRT IN RESECTED HEAD &amp; NECK CANCER

Gaztañaga, Miren; Miguel, I. San; Rodríguez, M. Fernández; Divasson, M. Pagola; Cambeiro, Mauricio; Moreno-Jiménez, Marta; Aristu, Javier; Montesdeoca, Néstor; Alcalde, Juan; Martı́nez-Monge, Rafael

doi:10.1016/s0167-8140(11)70411-x

Cited by 3 publications

(3 citation statements)

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“…Later, the techniques of intraoperative placed flaps and single shot radiation by means of individual dose painting methods also became available [ 123 , 124 ]. Due to these developments, it became possible to treat local tumor masses successfully with less toxicity compared to wide field EBRT [ 125 ] or reduce the radicality of surgical resections in order to preserve function [ 126 – 128 ]. Although intraoperative brachytherapy is an appealing interdisciplinary treatment alternative, higher complication rates in patients undergoing microvascular free tissue transfer have been reported.…”

Section: Intra- and Perioperative Implantations (Iobt And Pobt)mentioning

confidence: 99%

Modern head and neck brachytherapy: from radium towards intensity modulated interventional brachytherapy

Kovács¹

2014

jcb

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Intensity modulated brachytherapy (IMBT) is a modern development of classical interventional radiation therapy (brachytherapy), which allows the application of a high radiation dose sparing severe adverse events, thereby further improving the treatment outcome. Classical indications in head and neck (H&N) cancers are the face, the oral cavity, the naso- and oropharynx, the paranasal sinuses including base of skull, incomplete resections on important structures, and palliation. The application type can be curative, adjuvant or perioperative, as a boost to external beam radiation as well as without external beam radiation and with palliative intention. Due to the frequently used perioperative application method (intraoperative implantation of inactive applicators and postoperative performance of radiation), close interdisciplinary cooperation between surgical specialists (ENT-, dento-maxillary-facial-, neuro- and orbital surgeons), as well interventional radiotherapy (brachytherapy) experts are obligatory. Published results encourage the integration of IMBT into H&N therapy, thereby improving the prognosis and quality of life of patients.

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Section: Intra- and Perioperative Implantations (Iobt And Pobt)mentioning

confidence: 99%

Modern head and neck brachytherapy: from radium towards intensity modulated interventional brachytherapy

Kovács¹

2014

jcb

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“…In fact, in resected H&N cancer, the complication rates, locoregional failure, and disease-free survival were similar to limited-volume perioperative HDR-IRT and wide-field EBRT, despite a much smaller treatment volume. Careful delineation of the areas at high risk of recurrence may provide a useful basis for volume reduction and improve the therapeutic ratio [ 90 ].…”

Section: Resultsmentioning

confidence: 99%

Age Is Not a Limiting Factor in Interventional Radiotherapy (Brachytherapy) for Patients with Localized Cancer

Lancellotta

Kovács

Tagliaferri

et al. 2018

BioMed Research International

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This review examines the role of interventional radiotherapy (IRT otherwise known as brachytherapy) in cancer treatment for elderly patients. Despite their advanced age and associated comorbidities, elderly patients should receive definitive cancer therapies, including surgery and radiotherapy (RT). In fact, RT becomes first-line option for patients who are not eligible for surgery (due to comorbidities, anticoagulant drugs, and risk of disfigurement) or those who refuse it. It emerged from this review of the literature as effective, simple, safe, and comfortable and was associated with good local control, low toxicity rates, and excellent cosmesis and provided a cost benefit. IRT may be used as sole treatment for small cancers or as a useful adjunct to surgery or external beam radiotherapy (EBRT) in more advanced (or lymph node positive) cases, especially when the aim is local control with adequate preservation of normal tissue function. As palliative treatment, IRT preserves quality of life and/or improves survival. It is to be hoped that this review will serve as a helpful guide for members of multidisciplinary teams that are involved in treating elderly patients with cancer.

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“…Combined with a stereoscopic tracking camera, it could be used to guide surgeons during 125 I seed implantation. These developments have facilitated the successful treatment of local tumor masses, with reduced side effects compared with wide‐field EBRT, 7 and can reduce the radicality of surgical resections to preserve normal function 8‐10 . Currently, there are few studies which reported about the use of robot system in interstitial BT for malignant tumors in the head and neck regions.…”

Section: Introductionmentioning

confidence: 99%

A new multimodal, image‐guided, robot‐assisted, interstitial brachytherapy for the treatment of head and neck tumors–A preliminary study

Meng¹,

Xue²,

Qiao³

et al. 2020

Robotics Computer Surgery

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Background: Interstitial brachytherapy (BT) is becoming an accepted treatment option for head and neck cancer patients for whom surgery poses high risks. Multimodal, image-guided, robotic surgery has the potential to allow precise seed implantation into tumors. Our aim was to introduce a new multimodal, image-guided surgical robot during the performance of interstitial BT for the treatment of tumors in the head and neck regions. Methods: Clinical data for three patients were analyzed, retrospectively; patients had received 125 I seed implantations from July 2019 to October 2019. Multimodal, image-guided, robotic surgery was performed in all patients. Postoperative computed tomography data were imported to software to evaluate the accuracy of the seed position and the operation times. Results: The mean placement error of the 125 I seed was 1.9 ± 0.74 mm. The mean operation time is 47 minutes. Conclusion: The experimental results showed that the Remebot has promise for use during BT for the head and neck.

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289 oral LIMITED-VOLUME PERIOPERATIVE HDR BRACHYTHERAPY AS A SUBSTITUTE FOR WIDE-FIELD EBRT IN RESECTED HEAD & NECK CANCER

Cited by 3 publications

References 0 publications

Modern head and neck brachytherapy: from radium towards intensity modulated interventional brachytherapy

Modern head and neck brachytherapy: from radium towards intensity modulated interventional brachytherapy

Age Is Not a Limiting Factor in Interventional Radiotherapy (Brachytherapy) for Patients with Localized Cancer

A new multimodal, image‐guided, robot‐assisted, interstitial brachytherapy for the treatment of head and neck tumors–A preliminary study

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