(3-{[N-(5-Chloro-2-hydroxyphenyl)oxamoyl]amino}propyl)dimethylazanium perchlorate

Abstract

In the title compound, C13H19ClN3O3 +·ClO4 −, the 3-(di­meth­yl­ammonio)­propyl group of the cation is disordered over two sets of sites with occupancies 0.772 (6) and 0.228 (6). The cations are joined by pairs of N—H⋯O hydrogen bonds into centrosymmetric dimers and these dimers are assembled into chains along the a-axis direction, also through N—H⋯O hydrogen bonds. The perchlorate anions are linked to the hy­droxy groups of the cations by O—H⋯O hydrogen bonds. The positively charged ammonium groups and the anions give rise to folded layers parallel to the ab plane.

The Effect of Branched Alkyl Chain Length on the Properties of Supramolecular Organogels from Mono-N-Alkylated Primary Oxalamides

“…Given that many oxalamide compounds are biologically and pharmaceutically active [34][35][36][37][38][39][40][41][42][43][44][45], their effect on the metabolic activity of mammalian cells was evaluated. The effect of these compounds on the metabolism of bone marrow-derived mast cells (BMMCs) was evaluated using the XTT assay which measures the nicotinamide adenine dinucleotide phosphate (NADPH)-dependent bioreductase activity of live cells, a key mitochondrial process necessary for energy generation.…”

“…Oxalamide compounds are of considerable interest due to their potential in biomedical applications [34][35][36][37][38][39][40][41][42][43][44][45], catalysis [46][47][48], foods [49], and self-assembling behavior to form gels [50][51][52][53][54][55][56]. The oxalamide functional group consists of two amide groups next to each other in reverse mode, connected by two consecutive carbonyl groups, which has been extensively used as supramolecular synthon to generate LMWGs [50][51][52][53][54][55][56][57][58].…”