332 Finasteride for Recurrent Priapism in Children and Adolescents With Sickle Cell Disease (Scd). Report of 5 Cases

Barroso, Ubirajara; Marques, Thamy Cristine Santana; Novaes, Hugo

doi:10.1016/j.juro.2011.02.415

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2018

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“…In the case of this patient, though leuprolide was very well tolerated for an extended period of time, the choice was eventually made to transition to finasteride due to concerns about long term effects of hormonal manipulation. Finasteride, a 5α-reductase inhibitor, has been described as an effective prophylactic therapy for recurrent priapism, though the mechanism by which it acts in this context is unclear 5 . At the time of this report, the patient's priapism remains suppressed after several months of finasteride therapy in spite of discontinuation of leuprolide.…”

Section: Discussionmentioning

confidence: 99%

Case ‒ Temporary chemical castration in the management of recurrent priapism

Malaeb

2018

CUAJ

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Stuttering priapism entails repeated, distinct episodes of persistent penile erection despite interval periods of detumescence. While individual episodes are acutely treated, overall management of the patient with recurrent priapism focuses on prevention of future incidents. According to American Urological Association (AUA) guidelines, systemic therapy may be used for prevention of priapism — including hormonal agents, baclofen, digoxin, and terbutaline. Other methods of management include selfinjection of sympathomimetic agents and surgical intervention with placement of a penile prosthesis.1 This case report describes long-term use of hormonal therapy in the management of stuttering priapism in a young male.

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Section: Discussionmentioning

confidence: 99%

Case ‒ Temporary chemical castration in the management of recurrent priapism

Malaeb

2018

CUAJ

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332 Finasteride for Recurrent Priapism in Children and Adolescents With Sickle Cell Disease (Scd). Report of 5 Cases

Cited by 1 publication

References 0 publications

Case ‒ Temporary chemical castration in the management of recurrent priapism

Case ‒ Temporary chemical castration in the management of recurrent priapism

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