Abstract:Background: Post-asphyxial hypothermia is protective in experimental animals; however, there have been no RCT evaluating safety and effectiveness of whole body hypothermia in term infants with HIE.Objective: To assess safety and effectiveness of whole body hypothermia in term infants with moderate and severe HIE.Design/Methods: A RCT was conducted of infants 36 weeks GA admitted 6 h of age with either a) a cord or first (Ͻ1 hour) pH Ͻ7.0 or BD Ͼ16 mEq/dl or b) a perinatal event and need for resuscitation, AND … Show more
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