348 Effect of feed restriction and nature of forage on the mammary exfoliation rate in dairy cows

Hervé, Lucile; Veron, M.; Vanbergue, Elise; Quesnel, H.; Hurtaud, Catherine; Boutinaud, Marion

doi:10.2527/asasann.2017.348

Journal of Animal Science

2017

DOI: 10.2527/asasann.2017.348

|View full text |Cite

348 Effect of feed restriction and nature of forage on the mammary exfoliation rate in dairy cows

Lucile Hervé¹,

M. Veron²,

Elise Vanbergue³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2019

Publication Types

Select...

Article1

Relationship

Self Cite1

Independent0

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Feed restriction had no effect on plasma lactose concentration or milk Na + :K + ratio but increased milk Na + concentration; thus, we could not verify a clear effect on mammary epithelial integrity. During more severe feed restrictions (75% or less of control feed intake), in contrast, increases in mammary epithelium permeability have been observed (Stumpf et al, 2013;Herve et al, 2017b). In the present study, the MEC exfoliation rate at milking was positively correlated with the concentration of lactose measured before milking, milk Na + concentration, and the Na + :K + ratio in milk, suggesting again that MEC exfoliation is associated with disruption of the mammary epithelium.…”

supporting

confidence: 46%

Milk yield loss in response to feed restriction is associated with mammary epithelial cell exfoliation in dairy cows

Hervé

Quesnel

Veron

et al. 2019

Journal of Dairy Science

Self Cite

View full text Add to dashboard Cite

In dairy cows, feed restriction is known to decrease milk yield by reducing the number of mammary epithelial cells (MEC) in the udder through a shift in the MEC proliferation-apoptosis balance, by reducing the metabolic activity of MEC, or both. The exfoliation of MEC from the mammary epithelium into milk is another process that may participate in regulating the number of MEC during feed restriction. The aim of the present study was to clarify the mechanisms that underlie the milk yield loss induced by feed restriction. Nineteen Holstein dairy cows producing 40.0 ± 0.7 kg/d at 77 ± 5 d in milk were divided into a control group (n = 9) and a feed-restricted group (n = 10). Ad libitum dry matter intake (DMI) was recorded during a pre-experimental period of 2 wk. For 29 d (period 1), cows were fed either 100 (control) or 80% (feedrestricted) of their ad libitum DMI measured during the pre-experimental period. Then, all cows were fed ad libitum for 35 d (period 2). Milk production and DMI were recorded daily. Blood and milk samples were collected once during the pre-experimental period; on d 5, 9, and 27 of period 1; and on d 5, 9, and 30 of period 2. Mammary epithelial cells were purified from milk using an immunomagnetic method to determine the rate of MEC exfoliation. Mammary tissue samples were collected by biopsy at the end of each period to analyze the rates of cell proliferation and apoptosis and the expression of genes involved in synthesizing constituents of milk. Feed restriction decreased milk yield by 3 kg/d but had no effect on rates of proliferation and apoptosis in the mammary tissue or on the expression of genes involved in milk synthesis. The daily MEC exfoliation rate was 65% greater in feed-restricted cows than in control cows. These effects in feed-restricted cows were associated with reduced insulin-like growth factor-1 and cortisol plasma concentrations. When all cows returned to ad libitum feeding, no significant difference on milk yield or MEC exfoliation rate was observed between feed-restricted and control cows, but refeeding increased prolactin release during milking. These results show that the exfoliation process may play a role in regulating the number of MEC in the udders of dairy cows during feed restriction without any carryover effect on their milk production.

show abstract

supporting

confidence: 46%

Milk yield loss in response to feed restriction is associated with mammary epithelial cell exfoliation in dairy cows

Hervé

Quesnel

Veron

et al. 2019

Journal of Dairy Science

Self Cite

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

348 Effect of feed restriction and nature of forage on the mammary exfoliation rate in dairy cows

Cited by 1 publication

References 0 publications

Milk yield loss in response to feed restriction is associated with mammary epithelial cell exfoliation in dairy cows

Milk yield loss in response to feed restriction is associated with mammary epithelial cell exfoliation in dairy cows

Contact Info

Product

Resources

About