3D-CEUS tracking of injectable chemo-sonodynamic therapy-enabled mop-up of residual renal cell carcinoma after thermal ablation

Li, Cuixian; Zhu, Piao; Xiang, Huijing; Jin, Yunjie; Lu, Beilei; Shen, Yujia; Wang, Wenping; Huang, Beijian; Chen, Yu

doi:10.1016/j.mtbio.2022.100513

Cited by 7 publications

(1 citation statement)

References 56 publications

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“…Specifically, injectable thermosensitive hydrogels composed of hollow mesoporous organosilicon nanoparticles (Cur@HMON@gel) containing curcumin (Cur) have been identified as both biocompatible and biodegradable, transitioning from a colloidal sol state to an elastic gel matrix at physiological temperatures. The hydrogels discussed herein exhibit the ability to be specifically targeted to the tumor site for an extended duration exceeding two weeks, resulting in the comprehensive eradication of residual RCC lesions when subjected to ultrasound irradiation [ 115 ]. This approach addresses the limitation of incomplete tumor lesion elimination often encountered with thermal ablation techniques.…”

Section: Materials Used For Rcc Treatmentmentioning

confidence: 99%

Effective strategies to enhance the diagnosis and treatment of RCC: The application of biocompatible materials

Li,

Luo,

Liu

et al. 2024

Materials Today Bio

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Section: Materials Used For Rcc Treatmentmentioning

confidence: 99%

Effective strategies to enhance the diagnosis and treatment of RCC: The application of biocompatible materials

Li,

Luo,

Liu

et al. 2024

Materials Today Bio

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Engineering Sonosensitizer‐Derived Nanotheranostics for Augmented Sonodynamic Therapy

Yang,

Lv,

et al. 2024

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Sonodynamic therapy (SDT), featuring noninvasive, deeper penetration, low cost, and repeatability, is a promising therapy approach for deep‐seated tumors. However, the general or only utilization of SDT shows low efficiency and unsatisfactory treatment outcomes due to the complicated tumor microenvironment (TME) and SDT process. To circumvent the issues, three feasible approaches for enhancing SDT‐based therapeutic effects, including sonosensitizer optimization, strategies for conquering hypoxia TME, and combinational therapy are summarized, with a particular focus on the combination therapy of SDT with other therapy modalities, including chemodynamic therapy, photodynamic therapy, photothermal therapy, chemotherapy, starvation therapy, gas therapy, and immunotherapy. In the end, the current challenges in SDT‐based therapy on tumors are discussed and feasible approaches for enhanced therapeutic effects are provided. It is envisioned that this review will provide new insight into the strategic design of high‐efficiency sonosensitizer‐derived nanotheranostics, thereby augmenting SDT and accelerating the potential clinical transformation.

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Multi-target responsive nanoprobe with cellular-level accuracy for spatiotemporally selective photodynamic therapy

Fu,

Lu,

Zhang

et al. 2023

Microchim Acta

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3D-CEUS tracking of injectable chemo-sonodynamic therapy-enabled mop-up of residual renal cell carcinoma after thermal ablation

Cited by 7 publications

References 56 publications

Effective strategies to enhance the diagnosis and treatment of RCC: The application of biocompatible materials

Effective strategies to enhance the diagnosis and treatment of RCC: The application of biocompatible materials

Engineering Sonosensitizer‐Derived Nanotheranostics for Augmented Sonodynamic Therapy

Multi-target responsive nanoprobe with cellular-level accuracy for spatiotemporally selective photodynamic therapy

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