3D interleaved water and fat image acquisition with chemical-shift correction

Kwok, Wingchi E.; Tötterman, S.; Zhong, Jianhui

doi:10.1002/1522-2594(200008)44:2<322::aid-mrm21>3.0.co;2-q

Cited by 13 publications

(17 citation statements)

References 26 publications

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“…However, in these latter reports the method required acquisition of water and fat images from separate scans (as we did), thus diminishing the advantages in rapid scanning offered by spatial-spectral excitation. While simultaneous water and fat images were made possible for 2D SE and 2D GRE pulse sequences [26,36] only recently has simultaneous acquisition been made available for 3D GRE pulse sequences [24]. In a recent study, Kwok et al [24] reported on a 3D interleaved water and fat image-acquisition pulse sequence (known as 3-DIWFAC) as a means of acquiring fast, high SNR, 3D GRE water and fat images free of chemical shift.…”

Section: Discussionmentioning

confidence: 99%

“…Briefly, separate water-only and fatonly images are combined to produce a water+fat image that should be immune to phase-cancellation effects. Furthermore, if the fat-only image is acquired at a fat-centered frequency, the resulting image should be free of shadow misregistration as well (otherwise, the fat image must be shifted [24]). …”

Section: Chemical-shift Assessmentmentioning

confidence: 99%

“…Although new pulse sequences are constantly being developed for dealing with chemical-shift issues [22][23][24][25][26][27], the majority of clinical scanners employ only a standard set of manufacturer-supplied pulse sequences. Hence, there may be limited choices available for clinicians and investigators to study both the articular cartilage and subchondral bone in patients.…”

Section: Introductionmentioning

confidence: 99%

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Subchondral bone and cartilage thickness from MRI: effects of chemical-shift artifact

McGibbon

Bencardino

Palmer

2003

MAGMA Magnetic Resonance Materials in Physics, Biology and Medi

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Magnetic resonance imaging (MRI) is the modality of choice for visualizing and quantifying articular cartilage thickness. However, difficulties persist in MRI of subchondral bone using spoiled gradient-echo (SPGR) and other gradient-echo sequences, primarily due to the effects of chemical-shift artifact. Fat suppression techniques are often used to reduce these artifacts, but they prevent measurement of bone thickness. In this report, we assess the magnitude of chemical-shift effects (phase-cancellation and misregistration artifacts) on subchondral bone and cartilage thickness measurements in human femoral heads using a variety of pulse sequence parameters. Phase-cancellation effects were quantified by comparing measurements from in-phase images (TE=13.5 ms) to out-of-phase images (TE=15.8 ms). We also tested the assumption of the optimal in-phase TE by comparing thickness measures at small variations on TE (13.0, 13.5 and 14.0 ms). Misregistration effects were quantified by comparing measurements from water+fat images (water-only+fat-only images) to the measurements from in-phase (TE=13.5) images. A correction algorithm was developed and applied to the in-phase measurements and then compared to measurements from water+fat images. We also compared thickness measurements at different image resolutions. Results showed that both phase-cancellation artifact and misregistration artifact were significant for bone thickness measurement, but not for cartilage thickness measurement. Using an in-phase TE and correction algorithm for misregistration artifact, the errors in bone thickness relative to water+fat images were non-significant. This information may be useful for developing pulse sequences for optimal imaging of both cartilage and subchondral bone.

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Section: Discussionmentioning

confidence: 99%

Section: Chemical-shift Assessmentmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Subchondral bone and cartilage thickness from MRI: effects of chemical-shift artifact

McGibbon

Bencardino

Palmer

2003

MAGMA Magnetic Resonance Materials in Physics, Biology and Medi

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“…Another substantial concern is that the first three slices of the each imaging series (consistent for all series at all orientations) could not be resolved for subchondral bone. Pixel intensity of the surrounding fluid also increased toward the extremes of the imaging series, which suggests the presence of chemical‐shift artifact along the slice‐select direction (35). This effect was not analyzed in our study; therefore its impact on accuracy calculations is unknown.…”

Section: Discussionmentioning

confidence: 99%

“…Although the magnitude of chemical shift misregistration can be reduced by using a higher sampling bandwidth, its effect is still problematic when measuring thin structures such as the subchondral bone layer. The development of pulse sequences that inherently eliminate chemical‐shift artifact, such as that described by Kwok et al (35), could be potentially valuable in enabling the accurate measurement of both cartilage and subchondral bone defects.…”

Section: Discussionmentioning

confidence: 99%

Accuracy of cartilage and subchondral bone spatial thickness distribution from MRI

McGibbon

Bencardino

Yeh

et al. 2003

Magnetic Resonance Imaging

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Purpose: To assess three-dimensional measurement accuracy of articular cartilage (AC) and subchondral bone (SB) thickness from MRI. Materials and Methods:A computer program was used to calculate AC and SB thickness from MRI (three-dimensional spoiled gradient echo (SPGR), .31-mm resolution, 1-mm slice thickness) of six adult femoral heads. Specimens were imaged in five anatomical planes ranging between ϩ30°to -30°from neutral and cut into 2-mm thick sections along the five anatomical planes. Faxitron x-ray was used to produce microradiographic (.05-mm resolution) images of the sections. Results:In-plane measurement accuracy was .165 Ϯ .108 mm for AC thickness and .387 Ϯ .174 mm for SB thickness. Taking into account chemical-shift misregistration in SB thickness, accuracy of measurements improved to .213 Ϯ 128 mm. Out-of-plane (three-dimensional) thickness accuracy of the model, assessed by numerical simulation, was .015 mm. However, three-dimensional thickness errors in specimens were .319 Ϯ .256 mm for AC and .253 Ϯ .183 mm for SB thickness. Conclusion:Errors in three-dimensional AC thickness were attributed to volume-averaging effects caused by oblique intersection of the image plane with the joint surface. Errors in three-dimensional SB thickness were attributed to chemical-shift artifact. We conclude that accuracy of AC thickness is within clinically acceptable standards but that more sophisticated pulse sequences are needed to improve the measurement of SB thickness. MRI OFFERS A NONINVASIVE APPROACH to visualize and quantify the internal derangement of joint structures. Rheumatologic diseases, such as osteoarthritis (OA) or post traumatic articular injuries, can result in changes to the morphology of the articular cartilage (AC) and its underlying subchondral bone (SB). Detecting and monitoring changes in tissue morphology can play a critical roll in the management of patients with disease and/or injury to the articular tissues. MRI has shown great potential for this purpose.Early investigations of AC thickness measurement from MRI were generally performed on planar images, ignoring the effects of out-of-plane curvature (1-7). Neglecting out-of-plane curvature of the joint surfaces can lead to errors greater than 20% with moderately curved surfaces (8) and as high as 50% with strongly curved surfaces (9). Because longitudinal examinations cannot be easily controlled to ensure the image plane intersects the joint perpendicular to the surface, and at precisely the same location during each examination, these out-of-plane errors in thickness may lead to erroneous clinical assessments. Several investigators have developed postprocessing techniques that generate spatial thickness maps of AC, correcting for out-ofplane thickness overestimation (9 -14). However, none of these spatial mapping techniques has been rigorously validated for AC and SB.Losch et al (11) proposed a pixel-based "minimal distance algorithm" that finds the distance between each AC surface pixel and the closest AC/SB interface pixel. Haubner ...

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Interleaved water and fat dual-echo spin echo imaging with intrinsic chemical-shift elimination

Kwok

Tötterman

Zhong

2001

J. Magn. Reson. Imaging

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3D interleaved water and fat image acquisition with chemical-shift correction

Cited by 13 publications

References 26 publications

Subchondral bone and cartilage thickness from MRI: effects of chemical-shift artifact

Subchondral bone and cartilage thickness from MRI: effects of chemical-shift artifact

Accuracy of cartilage and subchondral bone spatial thickness distribution from MRI

Interleaved water and fat dual-echo spin echo imaging with intrinsic chemical-shift elimination

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