3D printed hollow microneedles array using stereolithography for efficient transdermal delivery of rifampicin

Yadav, Vivek; Sharma, Peeyush; Murty, Upadhyayula Suryanarayana; Mohan, Narayan H.; Thomas, R.; Dwivedy, Santosha K.; Banerjee, Subham

doi:10.1016/j.ijpharm.2021.120815

Cited by 64 publications

(29 citation statements)

References 33 publications

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“…Microneedles designed by VAT polymerization [180] or stereolithography [181] are small devices comprised of needles that measure less than 1000 µm which facilitate transdermal delivery by penetrating the stratum corneum [182]. Uddin et al fabricated microneedles using biocompatible polymers for cancer treatment via a combination of SLA and inkjet printing.…”

Section: Drug Delivery System (Dds)mentioning

confidence: 99%

High Precision 3D Printing for Micro to Nano Scale Biomedical and Electronic Devices

et al. 2022

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Three dimensional printing (3DP), or additive manufacturing, is an exponentially growing process in the fabrication of various technologies with applications in sectors such as electronics, biomedical, pharmaceutical and tissue engineering. Micro and nano scale printing is encouraging the innovation of the aforementioned sectors, due to the ability to control design, material and chemical properties at a highly precise level, which is advantageous in creating a high surface area to volume ratio and altering the overall products’ mechanical and physical properties. In this review, micro/-nano printing technology,mainly related to lithography, inkjet and electrohydrodynamic (EHD) printing and their biomedical and electronic applications will be discussed. The current limitations to micro/-nano printing methods will be examined, covering the difficulty in achieving controlled structures at the miniscule micro and nano scale required for specific applications.

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Section: Drug Delivery System (Dds)mentioning

confidence: 99%

High Precision 3D Printing for Micro to Nano Scale Biomedical and Electronic Devices

et al. 2022

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“…Firstly, computer-aided design (CAD) software was used for virtual design, and then the virtual model was input into a 3D printer. At last, 3D printing can provide high-throughput manufacturing of physical objects with high precision and reproducibility [60].…”

Section: The Manufacture Of Microneedlesmentioning

confidence: 99%

Advances of Microneedles in Biomedical Applications

Xuan

et al. 2021

Molecules

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A microneedle (MN) is a painless and minimally invasive drug delivery device initially developed in 1976. As microneedle technology evolves, microneedles with different shapes (cone and pyramid) and forms (solid, drug-coated, hollow, dissolvable and hydrogel-based microneedles) have been developed. The main objective of this review is the applications of microneedles in biomedical areas. Firstly, the classifications and manufacturing of microneedle are briefly introduced so that we can learn the advantages and fabrications of different MNs. Secondly, research of microneedles in biomedical therapy such as drug delivery systems, diagnoses of disease, as well as wound repair and cancer therapy are overviewed. Finally, the safety and the vision of the future of MNs are discussed.

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“…In the past 5 years, three-dimensional (3D) printing has attracted more and more attention in MNs manufacturing due to the multiplicity, accuracy, and superior reproducibility in the microscale [ 37 ]. A variety of 3D printing technologies are being developed, such as stereolithography (SLA), fused deposition modeling (FDM), liquid crystal display (LCD), selective laser sintering (SLS), and digital light processing (DLP) [ 38 – 40 ]. Economidou et al adopted the combination of 3D printing technology, MN, and MEMS to design a new device (3DMNMEMS) for controllable insulin delivery (Fig.…”

Section: Mns Used For Insulin Transdermal Deliverymentioning

confidence: 99%

Microneedle-based insulin transdermal delivery system: current status and translation challenges

Zhao¹,

Yao³

et al. 2021

Drug Deliv. and Transl. Res.

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3D printed hollow microneedles array using stereolithography for efficient transdermal delivery of rifampicin

Cited by 64 publications

References 33 publications

High Precision 3D Printing for Micro to Nano Scale Biomedical and Electronic Devices

High Precision 3D Printing for Micro to Nano Scale Biomedical and Electronic Devices

Advances of Microneedles in Biomedical Applications

Microneedle-based insulin transdermal delivery system: current status and translation challenges

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