“…To further safeguard crew-health, essential therapeutics that cannot be included in cargo due to restrictions such as shelf-life, are within scope 8 , 10 , 15 . For maximum fidelity of mission operations, a range of thermoplastic multi-purpose materials have been proposed for manufacturing of e.g., food processing equipment, surgical and medical supplies, radiation shielding, and habitat components 41 – 44 . Enabling technologies include: modular fermentations and bioprocesses at scale, optimized genetically engineered microbial strains to efficiently produce intermediates (i.e., ingredients, agents, crude polymer), and formulation/processing systems to assemble the final products (i.e., meals, drugs, manufactured items).…”