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Soriano, Francisco Garcia; Nogueira, Afonso César Rodrigues; Cappi, S; Lins, M; Gonzaga, L

doi:10.1186/cc2542

Cited by 4 publications

(2 citation statements)

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“…These abrupt changes caused surges in the FFT LF components, which reduced the overall accuracy of predicting subsequent deterioration and mortality. In another ICU study, Fourier spectral analysis of HR in combination with haemodynamic, echocardiographic, and serum cardiac markers was used for prognostication of patients suffering from sepsis [56]. In this investigation, consisting of 25 patients with septic shock, the mortality rate was 60%.…”

Section: Prognostication Of Infection With Heart Rate Variability Anamentioning

confidence: 99%

Clinical review: A review and analysis of heart rate variability and the diagnosis and prognosis of infection

et al. 2009

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Bacterial infection leading to organ failure is the most common cause of death in critically ill patients. Early diagnosis and expeditious treatment is a cornerstone of therapy. Evaluating the systemic host response to infection as a complex system provides novel insights: however, bedside application with clinical value remains wanting. Providing an integrative measure of an altered host response, the patterns and character of heart rate fluctuations measured over intervals-in-time may be analysed with a panel of mathematical techniques that quantify overall fluctuation, spectral composition, scale-free variation, and degree of irregularity or complexity. Using these techniques, heart rate variability (HRV) has been documented to be both altered in the presence of systemic infection, and correlated with its severity. In this review and analysis, we evaluate the use of HRV monitoring to provide early diagnosis of infection, document the prognostic implications of altered HRV in infection, identify current limitations, highlight future research challenges, and propose improvement strategies. Given existing evidence and potential for further technological advances, we believe that longitudinal, individualized, and comprehensive HRV monitoring in critically ill patients at risk for or with existing infection offers a means to harness the clinical potential of this bedside application of complex systems science.

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Section: Prognostication Of Infection With Heart Rate Variability Anamentioning

confidence: 99%

Clinical review: A review and analysis of heart rate variability and the diagnosis and prognosis of infection

et al. 2009

View full text Add to dashboard Cite

show abstract

“…[ 5 ] Some authors have reported that HRV may be an early predictor of septic shock and multiple organ dysfunction. [ 10 11 12 ] The aggressive inflammatory response observed in some patients infected with coronavirus can lead to myocardial ischemia in previously ill coronaries and also affect ventricular function in the early stages of sepsis. [ 12 ] We believe that the early characterization of a group of patients who progress to shock and multiple organ dysfunction with noninvasive physiological biomarkers will allow goal-oriented critical management strategies to be established that will offer targeted treatment to each patient.…”

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confidence: 99%