3T MRI in paediatrics: Challenges and clinical applications

Dagia, Charuta; Ditchfield, Michael

doi:10.1016/j.ejrad.2008.05.019

Cited by 76 publications

(90 citation statements)

References 27 publications

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“…Hepatic steatosis is diagnosed when the signal intensity of the liver decreases on opposed-phase images relative to that on in-phase images ( 16 ). At 3.0 T, T1 relaxation is prolonged, and this is different for various organs, with increases in T1 relaxation times of more than 70% for the kidney, 40% for the liver, and 20% for the spleen and fat ( 2 ). To maintain similar contrast to 1.5-T imaging, at 3.0 T it is important to use a longer repetition time to compensate for the prolonged T1 relaxation times of normal organs, and a shorter echo time is used to compensate for accelerated decay.…”

Section: T1-weighted Sequencesmentioning

confidence: 99%

MR Imaging of the Abdomen and Pelvis in Infants, Children, and Adolescents

Darge¹,

Anupindi²,

Jaramillo³

2011

Radiology

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Recent developments in magnetic resonance (MR) imaging have profoundly changed the investigation of abdominal and pelvic disease in pediatrics. Motion reduction techniques, such periodically rotated overlapping parallel lines with enhanced reconstruction, or PROPELLER, have resulted in reliable imaging with quiet breathing. Faster imaging sequences minimize artifact and allow for more efficient studies. Diffusion-weighted imaging has become increasingly important in the evaluation of neoplastic disease, depicting disease with increased cellularity and helping to differentiate benign from malignant masses. MR enterography helps visualize intra- and extraluminal bowel pathologic conditions. MR cholangiopancreatography can depict congenital and acquired causes of pancreatic and biliary abnormalities. MR urography is an effective technique for a one-stop-shop evaluation of structural urinary tract abnormality and renal function. Three-dimensional acquisitions allow volumetric display of structures from multiple angles. Specialized techniques allow quantification of iron and fat in the viscera in children with hemolytic anemia and obesity, respectively. This article covers current techniques and strategies to perform and optimize MR imaging of the abdomen and pelvis in infants, children, and adolescents and describes important practical applications.

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Section: T1-weighted Sequencesmentioning

confidence: 99%

MR Imaging of the Abdomen and Pelvis in Infants, Children, and Adolescents

Darge¹,

Anupindi²,

Jaramillo³

2011

Radiology

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“…Uncited refe Q2 rences [27,57,80] . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 …”

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“…Since MRI is highly sensitive to patient movement, this causes blurring and ghosting artifacts in the obtained images [31]. Besides, the anatomical structures are much smaller in size and not fully developed in babies, particularly in the brain (Dagia, 2008). The difference between a neonatal brain and adult brain is illustrated in Fig.…”

Section: Introductionmentioning

confidence: 98%

Neonatal brain MRI segmentation: A review

Devi¹,

Chandrasekharan²,

Sundararaman³

et al. 2015

Computers in Biology and Medicine

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“…To ensure a smooth variation of the flip angles, we added an L-2 regularisation term in the energy function. The T 1 value was restricted in the range of [1, 5000] ms based on prior knowledge [12]. The problem amounted to minimize the energy function for all voxels v in the whole volume V : (1) where M 0 is proportional to the equilibrium value of the magnetization, θ is the vector of the two flip angles, S T1 denotes the vector with the acquired two T 1 relaxometry signals, and F 1 (T 1 , θ) is the vector with the two simulated signals obtained from the equation [13] …”

Section: Qmri Statistic Template Constructionmentioning

confidence: 99%

Quantitative relaxation templates for the human brain at 3T

Cao

Commowick

Maumet

et al. 2014

2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI)

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The development of brain Magentic Resonance Imaging (MRI) is driving increasing demand for quantitative measurements. Quantitative MRI (qMRI) templates of relaxation times and proton density can be of particular interest for dedicated clinical applications such as characterizing brain tissue abnormalities, as well as general research purposes. In this paper, we have developed 3D qMRI statistical templates consisting of T 1 , T 2 , T * 2 and ρ * maps from the human brain at 3T. The qMRI templates were built from a population of 20 normal controls, for which individual maps were estimated in a robust manner, accounting for acquisition artifacts and expected relationships between the relaxometry parameters. For validation, we fed the qMRI templates into a realistic MRI simulator to synthesize MR-weighted images, and compared these images with the real MR acquisitions. High correlation coefficients (>0.80) show that the developed qMRI templates can be used as input dataset for MRI simulation community, which may be of great interest to clinical neuroscience field.

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3T MRI in paediatrics: Challenges and clinical applications

Cited by 76 publications

References 27 publications

MR Imaging of the Abdomen and Pelvis in Infants, Children, and Adolescents

MR Imaging of the Abdomen and Pelvis in Infants, Children, and Adolescents

Neonatal brain MRI segmentation: A review

Quantitative relaxation templates for the human brain at 3T

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