Fused pyridine derivatives R 0450 4-[(N-Imidazol-2-ylmethyl)anilino]pyranopyridine Analogues as Novel Antiangiogenic Agents. -A variety of [3,2-c]-, [3,2-b]-, [2,3-c]-and [2,3-b]pyranopyridines bearing an N-(imidazolylmethyl)aniline moiety at the 4-position are synthesized and evaluated for their primary anti-angiogenic properties. Among the synthesized compounds, 8-chloropyranopyridine (VIb) exhibits the most potent inhibitory activity. -(LEE, S.; CHAE, S. M.; YI, K. Y.; KIM, N.; OH*, C. H.; Bull. Korean Chem. Soc. 26 (2005) 4, 619-628; Dep. Chem., Hanyang Univ., Seoul 133-791, S. Korea; Eng.) -A. Forchert