Untitled

Fraser, Anna; Grimes, David A.

doi:10.1097/00006254-200304000-00022

Cited by 6 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although milk production increases maternal total energy expenditure by 15–25% (27,28), evidence for greater postpartum weight loss is equivocal (29). Prospective studies that measured maternal weights (not self-reported) before or during early pregnancy have generally reported lower postpartum weight retention at 1 year postpartum (30), more rapid loss approaching pregravid weight (31), or 1–2 kg greater weight losses within 3–6 months postpartum among lactating women (32).…”

Section: Discussionmentioning

confidence: 99%

Duration of Lactation and Incidence of the Metabolic Syndrome in Women of Reproductive Age According to Gestational Diabetes Mellitus Status: A 20-Year Prospective Study in CARDIA (Coronary Artery Risk Development in Young Adults)

et al. 2009

View full text Add to dashboard Cite

OBJECTIVEThe objective of the study was to prospectively assess the association between lactation duration and incidence of the metabolic syndrome among women of reproductive age.RESEARCH DESIGN AND METHODSParticipants were 1,399 women (39% black, aged 18–30 years) in the Coronary Artery Risk Development in Young Adults (CARDIA) Study, an ongoing multicenter, population-based, prospective observational cohort study conducted in the U.S. Women were nulliparous and free of the metabolic syndrome at baseline (1985–1986) and before subsequent pregnancies, and reexamined 7, 10, 15, and/or 20 years after baseline. Incident metabolic syndrome case participants were identified according to National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria. Complementary log-log models estimated relative hazards of incident metabolic syndrome among time-dependent lactation duration categories by gestational diabetes mellitus (GDM) adjusted for age, race, study center, baseline covariates (BMI, metabolic syndrome components, education, smoking, physical activity), and time-dependent parity.RESULTSAmong 704 parous women (620 non-GDM, 84 GDM), there were 120 incident metabolic syndrome case participants in 9,993 person-years (overall incidence rate 12.0 per 1,000 person-years; 10.8 for non-GDM, 22.1 for GDM). Increased lactation duration was associated with lower crude metabolic syndrome incidence rates from 0–1 month through >9 months (P < 0.001). Fully adjusted relative hazards showed that risk reductions associated with longer lactation were stronger among GDM (relative hazard range 0.14–0.56; P = 0.03) than non-GDM groups (relative hazard range 0.44–0.61; P = 0.03).CONCLUSIONSLonger duration of lactation was associated with lower incidence of the metabolic syndrome years after weaning among women with a history of GDM and without GDM, controlling for preconception measurements, BMI, and sociodemographic and lifestyle traits. Lactation may have persistent favorable effects on women's cardiometabolic health.

show abstract

Section: Discussionmentioning

confidence: 99%

Duration of Lactation and Incidence of the Metabolic Syndrome in Women of Reproductive Age According to Gestational Diabetes Mellitus Status: A 20-Year Prospective Study in CARDIA (Coronary Artery Risk Development in Young Adults)

et al. 2009

View full text Add to dashboard Cite

show abstract

“…Milk production increases maternal total energy expenditure by 15 %–25 % [24, 25], yet the association between lactation and greater weight loss is equivocal [38]. Prospective studies that measured maternal weights (not self-reported) from before or during early pregnancy have generally reported lower weight retention at 1 year postpartum [39], more rapid weight loss approaching pregravid weight [40], or 1–2 kg greater average weight loss within 3–6 months postpartum among lactating women [41].…”

Section: Lactation and Body Weight And Compositionmentioning

confidence: 99%

Impact of Breastfeeding on Maternal Metabolism: Implications for Women with Gestational Diabetes

Gunderson

2014

Curr Diab Rep

View full text Add to dashboard Cite

Lactating compared with nonlactating women display more favorable metabolic parameters, including less atherogenic blood lipids, lower fasting and postprandial blood glucose as well as insulin, and greater insulin sensitivity in the first 4 months postpartum. However, direct evidence demonstrating that these metabolic changes persist from delivery to postweaning is much less available. Studies have reported that longer lactation duration may reduce long-term risk of cardiometabolic disease, including type 2 diabetes, but findings from most studies are limited by self-report of disease outcomes, absence of longitudinal biochemical data, or no assessment of maternal lifestyle behaviors. Studies of women with a history gestational diabetes mellitus (GDM) also reported associations between lactation duration and lower the incidence of type 2 diabetes and the metabolic syndrome. The mechanisms are not understood, but hormonal regulation of pancreatic β-cell proliferation and function or other metabolic pathways may mediate the lactation association with cardiometabolic disease in women.

show abstract

“…The association between lactation and increased weight loss is equivocal, however lactation may result in metabolically beneficial changes in blood lipids, regional fat mobilization, and/or reduced insulin secretion and resistance that may prevent beta cell exhaustion. 13,14 The impact of lactation on maternal risk of NAFLD is unknown. Therefore, we sought to evaluate if a longer lactation duration was associated with a lower prevalence of NAFLD in mid-life.…”

Section: Introductionmentioning

confidence: 99%

Longer lactation duration is associated with decreased prevalence of non-alcoholic fatty liver disease in women

Ajmera

Terrault

VanWagner

et al. 2019

Journal of Hepatology

View full text Add to dashboard Cite

Background & Aims: Lactation lowers blood glucose and triglycerides, and increases insulin sensitivity. We hypothesized that a longer duration of lactation would be associated with lower prevalence of non-alcoholic fatty liver disease (NAFLD), which is the leading cause of chronic liver disease in the United States. Methods: Participants from the Coronary Artery Risk Development in Young Adults cohort study who delivered ≥ 1 child post-baseline (Y0: 1985–1986), and underwent CT quantification of hepatic steatosis 25 years following cohort entry (Y25: 2010–2011) were included (n = 844). The duration of lactation was summed for all post-baseline births, and NAFLD at Y25 was assessed by central review of CT images and defined by liver attenuation ≤ 40 Hounsfield Units after exclusion of other causes of hepatic steatosis. Unadjusted and multivariable logistic regression analyses were performed using an a priori set of confounding variables; age, race, education, and baseline body mass index. Results: Of 844 women who delivered after baseline (48% black, 52% white, mean age 49 years at Y25 exam), 32% reported lactation duration of 0 to 1 month, 25% reported >1 to 6 months, 43% reported more than 6 months, while 54 (6%) had NAFLD. Longer lactation duration was inversely associated with NAFLD in unadjusted logistic regression. For women who reported >6 months lactation compared to those reporting 0–1 month, the odds ratio for NAFLD was 0.48 (95% Cl 0.25–0.94; p = 0.03) and the association remained after adjustment for confounders (adjusted odds ratio 0.46; 95% Cl 0.22–0.97; p = 0.04). Conclusions: A longer duration of lactation, particularly greater than 6 months, is associated with lower odds of NAFLD in midlife and may represent a modifiable risk factor for NAFLD.

show abstract

Untitled

Abstract: After completion of this article, the reader will be able to compile the literature on the effect of lactation on maternal weight, to compare the various studies, and to summarize the data on the effect of lactation on maternal weight gain.

Cited by 6 publications

References 0 publications

Duration of Lactation and Incidence of the Metabolic Syndrome in Women of Reproductive Age According to Gestational Diabetes Mellitus Status: A 20-Year Prospective Study in CARDIA (Coronary Artery Risk Development in Young Adults)

Duration of Lactation and Incidence of the Metabolic Syndrome in Women of Reproductive Age According to Gestational Diabetes Mellitus Status: A 20-Year Prospective Study in CARDIA (Coronary Artery Risk Development in Young Adults)

Impact of Breastfeeding on Maternal Metabolism: Implications for Women with Gestational Diabetes

Longer lactation duration is associated with decreased prevalence of non-alcoholic fatty liver disease in women

Contact Info

Product

Resources

About