5-27-01 Neurological complications after renal transplantation, a local experience

Jost, Luis J.; Dávalos, M; Manes, Francisco; Leiguarda, R.; Merello, Marcelo; Esteguy, M.; Nogués, Martín

doi:10.1016/s0022-510x(97)86411-8

Cited by 2 publications

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“…1,5 Neurologic complications could be seen in up to 30% of recipients after renal transplantation in adults. [6][7][8][9][10] Neurologic complications can develop secondary to the transplantation itself, because of immunosuppressant medications used to prevent transplant rejection or because of the inherent disorders that led to transplantation, as well as a combination of all the above factors. 5 The range of indications for renal transplantation in pediatric patients differs from that in adults, and therefore a different spectrum of complications would be expected.…”

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Neurologic Complications Following Pediatric Renal Transplantation

et al. 2013

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We reviewed neurologic complications after renal transplantation in children over a 20-year period. Neurologic complications were classified as early (within 3 months) and delayed (beyond 3 months). Of 115 children, 10 (8.7%) had complications. Early complications were found in 4.35% of patients: seizures in 4 (posterior reversible leukoencephalopathy syndrome due to immunosuppressant toxicity, sepsis/presumed meningitis, and indeterminate) and headaches in 1. One patient with seizures received levetiracetam for 6 months and 1 with headaches received amitriptyline prophylaxis. Late complications were noted in 4.35% of patients: seizures in 3 (posterior reversible leukoencephalopathy syndrome due to hypertension, hypertensive encephalopathy), headaches in 2, and tremors in 1. Two patients with seizures were treated with anti-epilepsy medications; 1 with migraine received cyproheptadine prophylaxis. Neurologic complications develop in children after renal transplantation. Seizures due to posterior reversible leukoencephalopathy syndrome were the commonest complication. Early detection and appropriate management of these complications is important.

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Neurologic Complications Following Pediatric Renal Transplantation

et al. 2013

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“…We present a case of rapid evolution of severe SEL in a patient with NHL and GvHD on treatment with steroids. There are few descriptions of SEL in solid organ transplantation (7, 11–15). According to available data, cases of SEL in BMT setting have not been described, despite the wide use of prolonged courses of steroids for control of acute and chronic GvHD.…”

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confidence: 99%