50 Years Ago in CORR: Osteomalacia, Osteoporosis, and Calcium Deficiency B.E.C. Nordin, MD, MRCP, PhD 1960;17:235-258

Brand, Richard A.

doi:10.1007/s11999-011-1907-x

Clinical Orthopaedics &Amp; Related Research

2011

DOI: 10.1007/s11999-011-1907-x

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50 Years Ago in CORR: Osteomalacia, Osteoporosis, and Calcium Deficiency B.E.C. Nordin, MD, MRCP, PhD 1960;17:235-258

Richard A. Brand

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Cited by 2 publications

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Calcium revisited: part I

Burckhardt¹

2013

BoneKEy Reports

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In February 2013, the US Preventive Services Task Force (see www.uspreventiveservicestaskforce.org) recommended 'against daily supplementation with 400 IU or less of vitamin D3 and 1000, mg or less of calcium for the primary prevention of fractures in non institutionalized postmenopausal women', which illustrates the divergence of opinions. This review wants to shed an objective light on the importance of calcium for bone health. It cannot compete with an exhaustive analysis of the literature by an institute. It does not mention all significant references. But it highlights some pivotal studies from the past and it refers to recent studies that opened new views or added essential data to known facts. It also reflects the personal perception of the author. The first part deals mainly with intake, absorption, needs and recommendations; the second part will discuss the effects of calcium and its supplements on bone.

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Calcium revisited: part I

Burckhardt¹

2013

BoneKEy Reports

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Challenges in the Diagnosis of Magnesium Status

Workinger¹,

Doyle

Bortz³

2018

Nutrients

153

123

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Magnesium is a critical mineral in the human body and is involved in ~80% of known metabolic functions. It is currently estimated that 60% of adults do not achieve the average dietary intake (ADI) and 45% of Americans are magnesium deficient, a condition associated with disease states like hypertension, diabetes, and neurological disorders, to name a few. Magnesium deficiency can be attributed to common dietary practices, medications, and farming techniques, along with estimates that the mineral content of vegetables has declined by as much as 80–90% in the last 100 years. However, despite this mineral’s importance, it is poorly understood from several standpoints, not the least of which is its unique mechanism of absorption and sensitive compartmental handling in the body, making the determination of magnesium status difficult. The reliance on several popular sample assays has contributed to a great deal of confusion in the literature. This review will discuss causes of magnesium deficiency, absorption, handling, and compartmentalization in the body, highlighting the challenges this creates in determining magnesium status in both clinical and research settings.

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50 Years Ago in CORR: Osteomalacia, Osteoporosis, and Calcium Deficiency B.E.C. Nordin, MD, MRCP, PhD 1960;17:235-258

Cited by 2 publications

References 5 publications

Calcium revisited: part I

Calcium revisited: part I

Challenges in the Diagnosis of Magnesium Status

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