As the PCIe 6.0 specification places higher requirements on signal integrity and transmission latency, it becomes especially important to improve signal transmission performance at the physical layer of the transceiver interface. Retimer circuits are a key component of high-speed serial interfaces, and their delay and jitter size directly affect the overall performance of PCIe. For the typical retimer circuit with large-latency and low-jitter performance, this paper proposes a low-latency and low-jitter Retimer circuit based on CDR + PLL architecture for PCIe 6.0, using a jitter-canceling filter circuit to eliminate the frequency difference between the retiming clock and data, reduce the retiming clock jitter, and improve the quality of Retimer output data. The data are sampled using the retiming clock and then output, avoiding the problem of large penetration latency of typical retimer circuits. The circuit is designed using the CMOS 28 nm process. Simulation results show that when 112 Gbps PAM4 data are input to the retimer circuit, the Retimer penetration latency is 27.3 ps, which is 83.5% lower than the typical Retimer structure; the output jitter data are 741 fs, a 31.4% reduction compared to the typical retimer structure.