1975
DOI: 10.1016/0031-9422(75)85212-5
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6-Hydroxykynurenic acid from Thapsia villosa

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Cited by 8 publications
(8 citation statements)
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“…They are formed via kynurenine as a result of ring opening between C-2 and C-3 of tryptophan, catalysed by tryptophan oxygenase (11). 6-HKA was also found in higher plants (12,13). It was first isolated in tobacco leaves (4).…”
Section: Resultsmentioning
confidence: 99%
“…They are formed via kynurenine as a result of ring opening between C-2 and C-3 of tryptophan, catalysed by tryptophan oxygenase (11). 6-HKA was also found in higher plants (12,13). It was first isolated in tobacco leaves (4).…”
Section: Resultsmentioning
confidence: 99%
“…ttroduction Thapsia villosa L. has long been known as a vesicant containing plant [1] yet the study of its constituents has virtually been ignored, .only xanthotoxin [2], 6-methoxy-7-geranyloxycoumarin [3] and luteolin 7-glucoside [41 having been reported. Previous papers from this laboratory described the isolation and identification of 6-h~droxykynurenic [5] and abscisic acids, umbelliferone and scopoletin [6] from this plant, while an extensive chromatogra-Several of these compounds have now been isolated and their structures elucidated as the coumarins: umbelliprenin, 6-methoxy-7-geran yloxycoumarin,oxypeucedanin, oxypeucedanin hydrate, phellopterin, byakangelicin, and the phenols: salicylic, p-hydroxybenzoic, vanillic, p-coumaric, chlorogenic, neochlorogenic and 3,4-dimeth~x~cinnamic acids, p-hydroxybenzaldehyde, vanillin and ringal aldehyde.…”
Section: Thapsia Villosa Fruitsmentioning
confidence: 99%
“…Moreover, xanthurenic acid is known as a gametogenesis inducing factor of the malaria causing agent Plasmodium falciparum in mosquitoes. 11 Derivatives of 4-hydroxyquinoline-2-carboxylic acid [12][13][14][15] are also found in plants, for example 6-hydroxykynurenic acid in Gingko biloba. An important quorum sensing factor is the siderophore quinolobactin (8-hydroxy-4-methoxyquinoline-2-carboxylic acid) 8 from Pseudomonas fluorescens.…”
Section: Introductionmentioning
confidence: 99%
“…11 Biosynthetic studies demonstrated that thiocoralin is derived from tryptophan via kynurenic acid and quinaldic acid intermediates (Scheme 1). 11 Derivatives of 4-hydroxyquinoline-2-carboxylic acid [12][13][14][15] are also found in plants, for example 6-hydroxykynurenic acid in Gingko biloba. 14 The biological function in Gingko is unknown.…”
Section: Introductionmentioning
confidence: 99%