Liquid crystal substrates have been shown to provide the means to develop low-cost, reconfigurable, adaptive and tuneable microwave and MM-wave devices for mobile and wireless communication systems. However, techniques for the characterisation of materials, device fabrication and design are necessary in order to take maximum advantage of the possibilities that these materials offer. This includes appropriate modelling methods to simulate accurately the switching behaviour of the liquid crystal and the characteristics of the wave propagation through the devices, taking full consideration of the point-by-point variation of the material tensor permittivity. We describe these techniques here and show their application in the design of a meander-line phase shifter.