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Revanasiddappa, H. D.; Veena, Malligere A.

doi:10.2306/scienceasia1513-1874.2006.32.319

Cited by 8 publications

(4 citation statements)

References 5 publications

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“…Visible spectrophotometric methods based on diverse reactions have been proposed for the determination of MCP in pharmaceuticals [21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40]. MCP is a good electron donor, and procedures based on charge-transfer complex formation reactions with π acceptors such as chloranil and bromanil [21] have been reported.…”

Section: Table 1 Comparison Of the Performance Characteristics Of Thmentioning

confidence: 99%

“…Extractive spectrophotometric procedures based on an ion-pair complexation reaction with bromothymol blue [22], Mo (V) and Co (II) thiocyanates [23], have also been proposed. Other visible spectrophotometric methods based on reactions with p-dimethylaminocinnamaldehyde [24], p-dimethylaminobenzaldehyde and β-naphthol [25], 8-anilino-1-naphthalene sulfonic acid, resorcinol and β-naphthol [26], naphthoquinone, hydroquinone and resorcinol [27], imipramine hydrochloride [28] benzoylacetone [29], aniline [30], dibenzoylmethane [31], acetyl acetone [32], chromotropic acid and MBTH, [33] dicarboxypropylrhodanine [34], resorcinol [35], 4-aminosalicylic acid [36], sodium 1,2-naphthoquinone-4 sulfonate [37], folin-ciocalteu [38], sodium vanadate [39], and ammonium metavanadate [40] are also found in the literature. Most of the above visible spectrophotometric methods suffer from one or another disadvantage such as the use of organic solvents [22][23][24][29][30][31][32] or expensive reagent [33], poor sensitivity [21,23,24,32,34,37,39,40], the use of a heating [21,30,37,39,40] or extraction step …”

Section: Table 1 Comparison Of the Performance Characteristics Of Thmentioning

confidence: 99%

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Application of potassium permanganate to spectrophotometric assay of metoclopramide hydrochloride in pharmaceuticals

2012

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Two simple, sensitive, and cost-effective spectrophotometric methods are described for the determination of metoclopramide hydrochloride (MCP) in pharmaceutical dosage forms. The methods are based on a redox reaction between MCP and KMnO 4 in alkaline and acid media. Direct spectrophotometry (method A) involves treating MCP with permanganate in an NaOH medium and measuring a bluish green product at 610 nm. In indirect spectrophotometry (method B), MCP is treated with a fixed concentration of KMnO 4 in an H 2 SO 4 medium, and after a specified time, the unreacted KMnO 4 is measured at 545 nm. Under optimum assay conditions, Beer's law is obeyed over the ranges of 0.75-12.0 and 2.5-30.0 g/ml for methods A and B, respectively. Molar absorptivity values are calculated to be 2.33⋅10 4 and 2.66⋅10 4 l/mol cm for methods A and B, respectively, and corresponding Sandell's sensitivity values are 0.015 and 0.013 g/cm 2 . Limits of detection (LOD) and quantification (LOQ) are also reported. The applicability of the developed methods was demonstrated by the determination of MCP in tablet and injection forms. The accuracy and reliability of the proposed methods were further ascertained by recovery studies via standard addition technique.

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Section: Table 1 Comparison Of the Performance Characteristics Of Thmentioning

confidence: 99%

Section: Table 1 Comparison Of the Performance Characteristics Of Thmentioning

confidence: 99%

Application of potassium permanganate to spectrophotometric assay of metoclopramide hydrochloride in pharmaceuticals

2012

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“…where s is the standard error of the intercept and b is the slope of the calibration curve. (Revanasiddappa et. al., 2008).…”

Section: Optimization Of Conditionsmentioning

confidence: 99%

Spectrophotometric Determination of L-Ascorbic Acid in Pharmaceuticals based on Its Oxidation by Potassium Peroxydisulfate in the Presence of Ag(I) as a Catalyst

Amra Selimović,

Mirsad Salkić,

Halid Junuzović

2024

Int J Sci Res Chemi

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New accurate, precise, and sensitive spectrophotometric method were developed for the assay of L-ascorbic acid in pharmaceutical preparations. The determination of L-ascorbic acid was based on its oxidation by potassium peroxydisulfate in the presence of Ag(I) as a catalyst. The molar absorptivity of the proposed method was found to be 8.61 · 103 L mol-1 cm-1 at 248 nm. Beer's law was obeyed in the concentration range of 0.46–20.0 μg mL–1. Other compounds commonly found in vitamin C and multivitamin products did not interfere with the determination of L-ascorbic acid. The proposed method was successfully applied for the determination of L-ascorbic acid in pharmaceutical formulations. The results obtained with the proposed method showed good agreement with those given by the titrimetric method using iodine.

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“…Several methods have been reported for determination of the studied drugs in their pure forms, pharmaceutical preparations or biological fluids. These methods include titrimetric, spectrophotometric, spectrofluorimetric, electrochemical, chromatographic, electrophoresis, and chemiluminescence methods …”

Section: Introductionmentioning

confidence: 99%

Spectrofluorimetric determination of certain adrenergic agonist drugs in their pure forms and pharmaceutical formulations: Content uniformity test application

El‐Din

Attia

2016

Luminescence

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A new, simple, sensitive and rapid spectrofluorimetric method has been developed for determination of certain adrenergic agonists such as isoxsuprine hydrochloride, ritodrine hydrochloride and etilefrine hydrochloride in their pure forms and pharmaceutical dosage forms. The method depends on micellar enhancement of the native fluorescence of investigated drugs by using 2% w/v sodium dodecyl sulfate (SDS) as an anionic surfactant. The enhanced fluorescence intensity of investigated drugs was measured at 305 nm after excitation at 278 nm. The interaction of studied drugs with SDS was studied, and the enhanced fluorescence intensity was exploited to develop an assay method for the determination of investigated drugs. The relative fluorescence intensity-concentration plots were rectilinear over the range 0.15-3.00 μg ml , with low quantification limits of 0.132, 0.123 and 0.118 μg mL for isoxsuprine, ritodrine and etilefrine, respectively. The proposed method was successfully applied for determination of studied drugs in their pharmaceutical formulations. Moreover, the high sensitivity of the proposed method allows performing the content uniformity testing of the studied drugs in their tablets by using the official United States Pharmacopeia (USP) guidelines. Statistical comparisons of the results with those of the reported methods revealed excellent agreement and indicated no significant difference in accuracy and precision.

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Cited by 8 publications

References 5 publications

Application of potassium permanganate to spectrophotometric assay of metoclopramide hydrochloride in pharmaceuticals

Application of potassium permanganate to spectrophotometric assay of metoclopramide hydrochloride in pharmaceuticals

Spectrophotometric Determination of L-Ascorbic Acid in Pharmaceuticals based on Its Oxidation by Potassium Peroxydisulfate in the Presence of Ag(I) as a Catalyst

Spectrofluorimetric determination of certain adrenergic agonist drugs in their pure forms and pharmaceutical formulations: Content uniformity test application

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