7‐Tesla <scp>MR</scp> imaging of non‐melanoma skin cancer samples: correlation with histopathology

Aubry, S.; Leclerc, Olga; Tremblay, Luc; Rizcallah, Edmond; Croteau, Frédéric; Orfali, Charles; Lepage, Martin

doi:10.1111/j.1600-0846.2011.00587.x

Cited by 13 publications

(6 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…20 The use of MRI in dermatology remains experimental, although its potential for use has been noted in many publications since the 1990s. The image resolution of MRI makes it possible to differentiate the stratum corneum, the epidermis, and the dermis.…”

Section: -T Magnetic Resonance Imagingmentioning

confidence: 99%

Future Prospects in Dermatologic Applications of Lasers, Nanotechnology, and Other New Technologies

Boixeda

Feltes

Santiago

et al. 2015

Actas Dermo-Sifiliográficas (English Edition)

View full text Add to dashboard Cite

We review novel technologies with diagnostic and therapeutic applications in dermatology. Among the diagnostic techniques that promise to become part of dermatologic practice in the future are optical coherence tomography, multiphoton laser scanning microscopy, Raman spectroscopy, thermography, and 7-T magnetic resonance imaging. Advances in therapy include novel light-based treatments, such as those applying lasers to new targets and in new wavelengths. Devices for home therapy are also appearing. We comment on the therapeutic uses of plasma, ultrasound, radiofrequency energy, total reflection amplification of spontaneous emission of radiation, light stimulation, and transepidermal drug delivery. Finally, we mention some basic developments in nanotechnology with prospects for future application in dermatology.

show abstract

Section: -T Magnetic Resonance Imagingmentioning

confidence: 99%

Future Prospects in Dermatologic Applications of Lasers, Nanotechnology, and Other New Technologies

Boixeda

Feltes

Santiago

et al. 2015

Actas Dermo-Sifiliográficas (English Edition)

View full text Add to dashboard Cite

show abstract

“…High‐resolution magnetic resonance imaging (MRI), with dedicated surface coils has recently developed to study the skin, giving to this modality the ability to analyze its different layers . It allows visualizing not only anatomical information but also physical and chemical properties .…”

Section: Introductionmentioning

confidence: 99%

Edge detector‐based automatic segmentation of the skin layers and application to moisturization in high‐resolution 3 Tesla magnetic resonance imaging

Mesrar

Benhoumich

Miséry

et al. 2019

Skin Research and Technology

View full text Add to dashboard Cite

Introduction Previous studies have demonstrated the feasibility to explore moisturization with quantification imaging based on T2 mapping. The aim of this study was to describe and validate the first robust automated method to segment the first layers of the skin. Materials and Methods Data were picked from a previous study that included 35 healthy subjects who underwent a 3T MRI (multi spin echo calculation T2‐weighted sequence) with a microscopic coil on the left heel before and one hour after moisturization. The automatic algorithm was composed of the T2 map generation, a Canny filter, a selection of boundaries, and a local regression to delimitate stratum corneum, epidermis, and dermis. An automated affine registration was applied between the exams before and after moisturization. Results The failure rate of the algorithm was below 5%. Mean computation time was 139.12s. There was a significant and strong correlation between the automatic measurements and the manual ones for the T2 values (ρ: 0.905, P < 0.001) and for the thickness measurements (ρ: 0.8663; P < 0.001). For registration, mean of the Dice index was 0.64 [0.47; 0.80] and of the Hausdorff distance was 0.29 mm 95% CI: [0.28; 0.30]. Conclusion The proposed automatic method to study the first skin layers in 3T MRI using micro‐coils was robust and described T2 values and thickness measurements with a strong correlation to manual measurements. The use of an automated affine registration could also permit the generation of a mapping for a visual assessment of moisturization.

show abstract

“…Bittoun et al (1990) designed a dedicated surface gradient coil allowing an increase in resolution up to 70 9 390 lm² with 1.2 mm slice thickness in the direction perpendicular to the skin surface (13). The first comparisons of MR images to histology were reported by Bittoun et al (14,15). Skin lesions in humans and small animal models were investigated in vivo, in skin samples ex vivo, and in vitro for cell culture (16,17).…”

mentioning

confidence: 98%

“…Weis et al already achieved resolution of about 0.1 mm for human skin in vivo imaging (11) and demonstrated how MRI can be used for the general morphological characterization of the skin showing its three main layers (12). Bittoun et al (1990) designed a dedicated surface gradient coil allowing an increase in resolution up to 70 9 390 lm² with 1.2 mm slice thickness in the direction perpendicular to the skin surface (13 (14,15). Skin lesions in humans and small animal models were investigated in vivo, in skin samples ex vivo, and in vitro for cell culture (16,17).…”

mentioning

confidence: 99%

Phased‐array of microcoils allows MR microscopy of ex vivo human skin samples at 9.4 T

Göbel

Gruschke

Leupold

et al. 2014

Skin Research and Technology

View full text Add to dashboard Cite

show abstract

7‐Tesla MR imaging of non‐melanoma skin cancer samples: correlation with histopathology

Cited by 13 publications

References 20 publications

Future Prospects in Dermatologic Applications of Lasers, Nanotechnology, and Other New Technologies

Future Prospects in Dermatologic Applications of Lasers, Nanotechnology, and Other New Technologies

Edge detector‐based automatic segmentation of the skin layers and application to moisturization in high‐resolution 3 Tesla magnetic resonance imaging

Phased‐array of microcoils allows MR microscopy of ex vivo human skin samples at 9.4 T

Contact Info

Product

Resources

About