75-jähriger Patient mit rezidivierenden Hypoglykämien bei Insulinexzess

Abstract

Hirata syndrome is a rare differential diagnosis for recurrent hypoglycemia. This immune-mediated disease is associated with the formation of autoantibodies targeting insulin. Although the syndrome resolves spontaneously in the majority of patients, our case illustrates that individual patients require continuous immunosuppressive therapy.

The insulin autoimmune syndrome (IAS) as a cause of hypoglycaemia: an update on the pathophysiology, biochemical investigations and diagnosis

“…In conclusion, new informative cases of IAS in Caucasians continued to appear in the world literature [27,28,69,70,75,[90][91][92][93][94][95][96][97][98][99]. The very wide range of their clinical presentations and biochemical findings re-emphasised that IAS is a highly heterogeneous syndrome.…”