Based on the long fluorescence lifetime of upper laser level 4 I 13/2 of Er 3+ ions and high 1.5-1.6 µm laser operation efficiency, an Er 3+ :Yb 3+ :NaCe 0.43 Gd 0.57 (WO 4 ) 2 crystal was used to generate a Q-switched pulse laser with high energy and low threshold. End-pumped by a 970 nm diode laser, a passively Q-switched 1.5-1.6 µm pulse laser was first realized in an Er 3+ and Yb 3+ co-doped tungstate crystal, when a Co 2+ :Mg 0.4 Al 2.4 O 4 spinel crystal was used as saturable absorber. A 1.53 µm pulse laser with about 22 µJ energy, 76 ns duration and 21 kHz repetition rate was obtained at an absorbed pump power of 12 W in a c-cut 1.7-mm-thick Er 3+ :Yb 3+ :NaCe 0.43 Gd 0.57 (WO 4 ) 2 crystal. Keywords: 1.53 µm pulse laser, passive Q-switching, Er 3+ :Yb 3+ :NaCe 0.43 Gd 0.57 (WO 4 ) 2 crystal, Co 2+ :Mg 0.4 Al 2.4 O 4 crystal