89Addition of dexmedetomidine to prilocaine for intravenous regional anaesthesia

Arslan, Gülten; Yeter, Hacer; Süslü, Hüsnü; Erkal, Hakan; Özyurt, Yaman; Temizel, Feriha; Arıykan, Z.

doi:10.1016/j.rapm.2006.06.138

Cited by 3 publications

(1 citation statement)

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“…A study comparing intrathecal dexmedetomidine with intrathecal clonidine in patients undergoing transurethral urological surgery found that dexmedetomidine offered no additional benefit in terms of duration of sensory blockade or postoperative analgesia requirements [89]. Dexmedetomidine does seem to provide prolonged postoperative analgesia when used as an additive to an LA in total intravenous anaesthesia [90, 91]. Further work is necessary to quantify whether dexmedetomidine offers a significant clinical benefit over clonidine as neurotoxicity has been observed in rabbits receiving epidural dexmedetomidine [92].…”

Section: Adjuvants To Local Anaestheticsmentioning

confidence: 99%

Local anaesthetics and adjuvants – future developments

Wiles¹,

Nathanson²

2010

Anaesthesia

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Summary The introduction of local anaesthesia some years after the first public demonstration of general anaesthesia not surprisingly created less excitement and interest amongst both the public and the medical profession. However, in its own way, a new revolution was happening. Local anaesthesia produced an increase in the choice of anaesthetic techniques available to practitioners and patients. In common with general anaesthesia, the choice of agents remained very limited for the first six decades, and interest in the practice of local, regional or central neuraxial blockade and the development of new techniques and drugs were hampered by perceived safety issues even as late as the second half of the 20th century. It is only in the last few years that, with an apparent renaissance in the use of local anaesthesia, the pace of development has picked up. As the use and range of techniques has increased, so has interest in solving some of the longstanding problems with the available drugs.

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Section: Adjuvants To Local Anaestheticsmentioning

confidence: 99%