99M o/99m Tc chromatographic column generator based on cerium(IV) molybdate gel

Preparation and characterization of cerium(IV) tellurium molybdate gel and its application as a bed for chromatographic ⁹⁹Mo/^99mTc generator

“…Thus, the average 99m Tc elution yield for CeTeMo gel is slightly higher than that for CeMo gel (75.4 %). 9 Sharp elution peaks were obtained with the flow rates of 0.25, 0.5 and 0.75 (the most sharp one was obtained with the flow rate of 0.75 ml min -1 ), while a relatively broad one was obtained with the flow rate of 1 ml min -1 . A maximum percent fraction of 99m Tc activity was obtained at the 2 nd ml of eluate for the flow rates of 0.25, 0.5 and 1 ml min -1 (49.7, 54.1 and 33.1 %, respectively), while it was obtained at the 1 st ml of eluate for the flow rate of 0.75 ml min -1 (82.5 %).…”

“…21,23 The thermal gravimetric behavior of CeTeMo gel resembles to a great extent that of cerium(IV) molybdate (CeMo) gel. 9 Energy dispersive X-ray (EDX) spectrometric elemental analysis indicated that the prepared gel material incorporated ~27 % (wt./wt.) of molybdenum.…”

“…1 Criteria for good gel generators include high-content of 99 Mo in the gel bed, highelution yield and high radionuclidic, radiochemical and chemical purities of the 99m Tc eluates. Many gel materials, including acidic salts of polyvalent metals and salts of heteropolyacids, have been used as beds for 99 Mo/ 99m Tc generators, e.g., zirconium molybdate, [2][3][4][5][6] stannic molybdate, 7 titanium molybdate, 8 cer ium (I V) molybdate, 9 12-molybdocerate (I V), 10 6tungstocerate(IV) 11 magnesium molybdate 12 and zirconium molybdophosphate. 13 Zirconium molybdate is the most famous material used as a bed for 99 Mo/ 99m Tc generators, but the synthesis and study of other gel materials constitute a renewable research filed in literature to obtain more alternatives.…”

“…In addition, adding a small ratio of tellurium (IV) was found to increase the 99 Mo uptake by the formed gel comparing with the case of CeMo gel. 9 This work aims at the preparation of cerium(IV) tellurium molybdate gel material containing a high content of molybdenum which can be used as a new bed material for a chromatographic 9 9 Mo / 9 9 m Tc radioisotope generator of a good performance.…”

Preparation and performance of 99Mo/99mTc chromatographic column generator based on zirconium molybdosilicate

“…Although ( , ) 99 Mo has a lower specific activity (< 10 Ci/g) [8], it has many advantages where simple equipment is needed for processing, radionuclidic contamination is limited by the target purity (especially for 98 Mo enriched targets) and the produced radioactive waste is minimal. [4] or secondly by incorporation of Mo into gel materials [e. g., 12-molybdocerate, 6-tungstocerate, stannic molybdate, titanium molybdate, zirconium molybdate, zirconium molybdophosphate, alumina molybdate, cerium(IV) molybdate, cerium(IV) tellurium molybdate] via precipitation reactions using the post-irradiation method or the less-common pre-irradiation method [9][10][11][12][13][14][15][16][17], (ii) Extraction generators including solvent extraction (conventional or aqueous biphasic system), solid phase extraction generators, extraction chromatographic generators and supported liquid membrane generators (as a modified version of extraction chromatography) (iii) sublimation and thermochromatographic generators and (iv) electrochemical generators [4].…”