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Cefali, Eugenio A.; Nolan, Joseph C.; McConnell, Will; Walters, Denise Lowe

doi:10.1023/a:1016291228957

Cited by 26 publications

(6 citation statements)

References 8 publications

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“…Vzygula et al [45] have used natural zeolite for animal diet use in order to make better the eggs quality, and the zeolite application for medicine adsorption to neutralize the injurious effect of toxic swallow ingredients has been done by Kececi et al [46]. Nevertheless, there are not many works studying the relationship between biologically lively molecules and zeolite synthetic as the subsidiary therapy of hematologic disorder [47]. Recently, the zeolite membranes and crystals have been hydrothermally synthesized as biomaterials for drug-delivering [48].…”

Section: Drug-delivering Biomaterialsmentioning

confidence: 99%

Zeolite-based biomaterials for biomedical application: A review

Purnomo

Setyarini

Sulistyaningsih

2018

AIP Conference Proceedings

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Abstract. This review focuses on the latest reports of the use of zeolites, natural as well as synthetic, as biomedical materials. Discussion on biocompatibility, non-toxicity, zeolite for drug delivery materials, zeolite for bone implants and implant coatings, and the mechanical properties of polymer-zeolite composites are included. The section on the interaction between body tissues and zeolite-based biomaterials focuses on their biocompatibility, non-toxicity, and bioactivity. The next section concerns drug delivering biomaterials. Including delivery of a controlled drug, ionic removal, and synthesized drug delivering materials. The final section concern bone graft substitutes and implant-coating to improve corrosion resistance and osteointegration. The implant material system discussed in a further section is an investigation of the mechanical properties of high-density polyethylene(HDPE)-zeolite composites developed as skull bone implant materials.

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Section: Drug-delivering Biomaterialsmentioning

confidence: 99%

Zeolite-based biomaterials for biomedical application: A review

Purnomo

Setyarini

Sulistyaningsih

2018

AIP Conference Proceedings

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“…During the last two decades of the twentieth century a variety of in vitro and in vivo studies have been performed on animal models, mostly using laboratory rodents (mice and rats), but also Beagle breed of dogs (25,(44)(45)(46) as well as Quarter breed of horses (42,47) as the most common companion animal species in order to evaluate the effects of orally applied CPL on their health status and performance (Table 1).…”

Section: Companion Animals and Horsesmentioning

confidence: 99%

Zeolite clinoptilolite nanoporous feed additive for animals of veterinary importance: potentials and limitations

et al. 2017

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I n the past two decades many substances of natural or synthetic origin were studied as potential alternatives to antibiotic growth promoters (AGP) and some of them, particularly immunomodulators (IMs) and nutraceuticals (NCs), have shown to be capable of stimulating functions of the immune system and improving general health. At the same time, they were shown to be harmless for animals and the environment. Promising results have been obtained with natural clay minerals, zeolites among which clinoptilolite (CPL) is the best known as zootechnical and biomedical feed ingredient widely reported in scientific literature and used in farm animal nutrition. CPL has a potential to replace AGP due to its unique anti-bacterial properties, safety and efficacy as dietary supplement in food animals unifying potentials of an IM and NC. Currently, there INTRODUCTIONT he phrase "survival of the fittest" as an alternative to "natural selection" has been adopted and published in 1868 by Charles Darwin (1), and nowadays is becoming so true because of the rapid emergence of antibiotic resistant strains of pathogenic microbes of biomedical, particularly veterinary importance. This is a consequence of non-clinical use and misuse of dietary antibiotics for more than sixty years to prevent bacterial infections and to enhance performance in livestock production, mostly in chickens and pigs (2). Namely, the increased sanitary problems in intensive farming of food animals have been overcome thus far by adding sub-therapeutic doses of antibiotic growth promoters (AGP) infeed to enhance production efficiency by increasing growth rate, improv- ing feed utilization and reducing mortality from clinical disease is well documented particularly in swine production systems (3). However, the consumers especially in developed countries are becoming increasingly concerned about drug residues in meat and other animal products (4). In addition, it has been suggested that the continuous use of antibiotics may contribute to a reservoir of drugresistant bacteria (5) which may be capable of transferring their resistance to pathogenic bacteria in both animals and humans (6). As a result, many countries have banned or are banning the inclusion of antibiotics in diets as a routine means of growth promotion. The first experience of an AGP ban in Sweden in 1986 indicated a reduction in growth and an increase in morbidity and mortality rates in weaned pigs, which emphasized the importance of antibiotic use in intensive swine production(7). The total ban of dietary AGP in the EU countries since January 1, 2006 (EU Regulation No. 1831 and the elimination of their use in animal feed and water in the USA effective January 1, 2017 (FDA, CVM 2012, VFD Basics 2017) has had a serious influence on both health and performance of food animals underlining the need to develop alternative dietary and non-dietary strategies to evaluate the potential antimicrobial agents for their replacement (8). According to the World Health Organization, most antibiotics will not ...

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“…Besides FAU and EMT, zeolite types of BEA, LTI, MFI, and MOR are some of the other industrially most important framework types. 2 In biological and medical fields, the use of zeolites dates back to the early 1990s, when the capability of FAU (X, Y), LTA (Linde Type A, zeolite A), and MOR frameworks to be applied as magnetic resonance imaging (MRI) contrast agents and/ or bactericidal agents 30,31 along with their potential for dental or pharmacological applications 32,33 were realized. Since then, advances in synthesis of different zeolitic frameworks have progressively paved the way for expanding their exploitation in biomedical research and industry sectors.…”

Section: High Throughput Methods For Fabrication Of Zeolitic Porous Bmentioning

confidence: 99%

<p>Biomedical Applications of Zeolitic Nanoparticles, with an Emphasis on Medical Interventions</p>

Derakhshankhah¹,

Jafari²,

Sarvari³

et al. 2020

IJN

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The advent of porous materials, in particular zeolitic nanoparticles, has opened up unprecedented putative research avenues in nanomedicine. Zeolites with intracrystal mesopores are low framework density aluminosilicates possessing a regular porous structure along with intricate channels. Their unique physiochemical as well as physiological parameters necessitate a comprehensive overview on their classifications, fabrication platforms, cellular/ macromolecular interactions, and eventually their prospective biomedical applications through illustrating the challenges and opportunities in different integrative medical and pharmaceutical fields. More particularly, an update on recent advances in zeolite-accommodated drug delivery and the prevalent challenges regarding these molecular sieves is to be presented. In conclusion, strategies to accelerate the translation of these porous materials from bench to bedside along with common overlooked physiological and pharmacological factors of zeolite nanoparticles are discussed and debated. Furthermore, for zeolite nanoparticles, it is a matter of crucial importance, in terms of biosafety and nanotoxicology, to appreciate the zeolite-bio interface once the zeolite nanoparticles are exposed to the biomacromolecules in biological media. We specifically shed light on interactions of zeolite nanoparticles with fibrinogen and amyloid beta which had been comprehensively investigated in our recent reports. Given the significance of zeolite nanoparticles' interactions with serum or interstitial proteins conferring them new biological identity, the preliminary approaches for deeper understanding of administration, distribution, metabolism and excretion of zeolite nanoparticles are elucidated.

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Untitled

Cited by 26 publications

References 8 publications

Zeolite-based biomaterials for biomedical application: A review

Zeolite-based biomaterials for biomedical application: A review

Zeolite clinoptilolite nanoporous feed additive for animals of veterinary importance: potentials and limitations

<p>Biomedical Applications of Zeolitic Nanoparticles, with an Emphasis on Medical Interventions</p>

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