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doi:10.15741/revbio.04.03.03

Cited by 3 publications

(5 citation statements)

References 19 publications

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“…Pure propiconazole was obtained as a colorless oil containing both diastereoisomers. First diastereoisomer 1…”

Section: Resultsmentioning

confidence: 99%

“…This encouraged the intensive use of pesticides, many of which are synthetic and with a very high efficiency. Nevertheless, as time went by, there have been observed serious environmental effects as a consequence of the use of such chemicals [1]. Due the continuous growth of the population, there is a critical necessity of getting a better food production and maintain the food safety worldwide.…”

Section: Introductionmentioning

confidence: 99%

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Propiconazole nanoencapsulation in biodegradable polymers to obtain pesticide controlled delivery systems.

et al. 2019

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The nanoencapsulation of pesticides in biodegradable polymers confers several advantages to conventional agrochemicals, such as protection against losses due volatilization and degradation of the active ingredient, as well as the augment of water dispersion, allowing for their application on crops without requiring the use of organic solvents that could harm the user and the environment. This characteristics could enhance the productivity, reducing both costs and environmental pollution. In this work the propiconazole fungicide, forming part of a commercial formulation as well as in its pure state, was encapsulated using as carriers the biodegradable polymer poly lactic acid (PLA) and the biodegradable co-polymer poly (lactic-co-glicolic) acid, all with the aim of generate controlled fungicide release systems to augment the efficiency of the treatments of the Fusarium dieback disease. The most efficient system obtained presented nanospheres of 146.28 nm and an encapsulation efficiency over 42%. The antifungal activity tests showed that the use of this nanoencapsulated fungicide system enhances the growth inhibition percentage in 5%, obtaining a formulation that presents good dispersion in water without the need of organic emulsifier agents.

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“…Pure propiconazole was obtained as a colorless oil containing both diastereoisomers. First diastereoisomer 1…”

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Propiconazole nanoencapsulation in biodegradable polymers to obtain pesticide controlled delivery systems.

et al. 2019

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“…Several examples of nanopesticides have been quoted in published literature (Kah et al, 2013;Perlatti et al, 2013;Kah and Hofmann, 2014;Kookana et al, 2014;Cano Robles and Mendoza Cant u, 2017). However, a clear and agreed definition of nanopesticide is currently not available, 37 and many of the publications have regarded products containing particles ranging from the typical nanoscale (between 1 and 100 nm) to much larger sizes (up to 1,000 nm) as nanopesticides.…”

Section: E2 Recommended Guidance For Nanomaterials Pesticidesmentioning

confidence: 99%

“…This literature search also resulted in the highest number of records for nanoencapsulates, silver and titanium dioxide and showed that food additives and FCM are the most frequently indicated applications. Future developments are expected in the field of nanoencapsulates and nano-composites in applications such as novel foods, food/feed additives, biocides, FCM, and especially pesticides (Kah et al, 2013;Perlatti et al, 2013;Kah and Hofmann, 2014;Kookana et al, 2014;Cano Robles and Mendoza Cant u, 2017;Chaudhry et al, 2017). As mentioned in the conclusions of the 2011 SC Guidance, it will require updating to stay aligned with innovations and fast developments in this area.…”

Section: 1mentioning

confidence: 99%

“…The developments in the field of nanosized active ingredients and formulations have also opened up new avenues for enhancing the delivery and efficacy of pesticides and other agrochemicals (not necessarily in the remit of EFSA). The expected worldwide use of nanopesticides in the future may contribute to a reduction in overall pesticide use through enhanced efficacy and better control of applications in the field as well as better stability of the dispersions, and slow-or controlled-release of the active ingredients (Perlatti et al, 2013;Kah and Hofmann, 2014;Cano Robles and Mendoza Cant u, 2017).…”

Section: E2 Recommended Guidance For Nanomaterials Pesticidesmentioning

confidence: 99%

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Guidance on risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain: Part 1, human and animal health

Hardy¹,

Benford²,

Halldórsson³

et al. 2018

EFS2

170

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The European Food Safety Authority has produced this Guidance on human and animal health aspects (Part 1) of the risk assessment of nanoscience and nanotechnology applications in the food and feed chain. It covers the application areas within EFSA's remit, e.g. novel foods, food contact materials, food/feed additives and pesticides. The Guidance takes account of the new developments that have taken place since publication of the previous Guidance in 2011. Potential future developments are suggested in the scientific literature for nanoencapsulated delivery systems and nanocomposites in applications such as novel foods, food/feed additives, biocides, pesticides and food contact materials. Therefore, the Guidance has taken account of relevant new scientific studies that provide more insights to physicochemical properties, exposure assessment and hazard characterisation of nanomaterials. It specifically elaborates on physicochemical characterisation of nanomaterials in terms of how to establish whether a material is a nanomaterial, the key parameters that should be measured, the methods and techniques that can be used for characterisation of nanomaterials and their determination in complex matrices. It also details the aspects relating to exposure assessment and hazard identification and characterisation. In particular, nanospecific considerations relating to in vivo/in vitro toxicological studies are discussed and a tiered framework for toxicological testing is outlined. It describes in vitro degradation, toxicokinetics, genotoxicity as well as general issues relating to testing of nanomaterials. Depending on the initial tier results, studies may be needed to investigate reproductive and developmental toxicity, immunotoxicity, allergenicity, neurotoxicity, effects on gut microbiome and endocrine activity. The possible use of read-across to fill data gaps as well as the potential use of integrated testing strategies and the knowledge of modes/mechanisms of action are also discussed. The Guidance proposes approaches to risk characterisation and uncertainty analysis, and provides recommendations for further research in this area.

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Guidance on risk assessment of nanomaterials to be applied in the food and feed chain: human and animal health

More¹,

Bampidis²,

Benford³

et al. 2021

EFS2

138

126

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The EFSA has updated the Guidance on risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain, human and animal health. It covers the application areas within EFSA's remit, including novel foods, food contact materials, food/feed additives and pesticides. The updated guidance, now Scientific Committee Guidance on nano risk assessment (SC Guidance on Nano-RA), has taken account of relevant scientific studies that provide insights to physico-chemical properties, exposure assessment and hazard characterisation of nanomaterials and areas of applicability. Together with the accompanying Guidance on Technical requirements for regulated food and feed product applications to establish the presence of small particles including nanoparticles (Guidance on Particle-TR), the SC Guidance on Nano-RA specifically elaborates on physico-chemical characterisation, key parameters that should be measured, methods and techniques that can be used for characterisation of nanomaterials and their determination in complex matrices. The SC Guidance on Nano-RA also details aspects relating to exposure assessment and hazard identification and characterisation. In particular, nanospecific considerations relating to in vitro/in vivo toxicological studies are discussed and a tiered framework for toxicological testing is outlined. Furthermore, in vitro degradation, toxicokinetics, genotoxicity, local and systemic toxicity as well as general issues relating to testing of nanomaterials are described. Depending on the initial tier results, additional studies may be needed to investigate reproductive and developmental toxicity, chronic toxicity and carcinogenicity, immunotoxicity and allergenicity, neurotoxicity, effects on gut microbiome and endocrine activity. The possible use of read-across to fill data gaps as well as the potential use of integrated testing strategies and the knowledge of modes or mechanisms of action are also discussed. The Guidance proposes approaches to risk characterisation and uncertainty analysis.

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Untitled

Cited by 3 publications

References 19 publications

Propiconazole nanoencapsulation in biodegradable polymers to obtain pesticide controlled delivery systems.

Propiconazole nanoencapsulation in biodegradable polymers to obtain pesticide controlled delivery systems.

Guidance on risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain: Part 1, human and animal health

Guidance on risk assessment of nanomaterials to be applied in the food and feed chain: human and animal health

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